Protein Alignment Ns4 and Gnl3l

DIOPT Version :10

• Sequence 1: NP_610055.1
• Gene: Ns4 / 35338
• FlyBaseID: FBgn0032882
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_001075427.1
• Gene: Gnl3l / 100034253
• RGDID: 1600217
• Length: 577
• Species: Rattus norvegicus
• Alignment Length: 494
• Identity: 119/494 - (24%)
• Similarity: 200/494 - (40%)
• Gaps: 137/494 - (27%)

  Fly    78 KKELEQMKQEGFKPFEKLSPAQREVDDRYFAGCDFPVRPPWTLTESKEELDRTENRYFKEYVDEL 142
            ||.:|:|:       ||...|:                          |.:|..:|..:.|..::
  Rat    54 KKRVEEMR-------EKQQVAR--------------------------EQERQRHRTMESYCQDV 85

  Fly   143 QKKQRAGDSKELSLFELNL------ETWRQLW-----RVLEFSDILLIIVDVRYATLMFPP---- 192
            .|:|:..:.||..|.|||:      |..|:.:     :|:|:||::|.::|.|      .|
  Rat    86 LKRQQEFEQKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDAR------DPLGCR 144

  Fly   193 --SLYDYIINTL-KKHAIVVFNKVDLVEPHAVVAWRQYFRDRYPQLPVVLFASFLPRSRKGSQRG 254
              .:.:.::... .|..::|.||:|||....|..|.:|.|:   :||.|.|           :..
  Rat   145 CFQMEETVLRAEGNKKLVLVLNKIDLVPKEIVEKWLEYLRN---ELPTVAF-----------KAS 195

  Fly   255 PQAHRRSMEGVYNIYKECQRYVQGEVDLTTWEQKIREDMRSDQLDILDEISTAVEGELKISSSID 319
            .|.|:     |.|:.: |               |:..|..|:.| :..:.....|..:::..:
  Rat   196 TQHHQ-----VKNLTR-C---------------KVPVDQASESL-LKSKACFGAENLMRVLGN-- 236

  Fly   320 TTPHEHVKYHSGVLTIGCIGFPNVGKSSLINALKGRKVVSVSRTPGHTKHFQTIFLTPLVRLCDC 384
               :..:....|.:.:|.:|.||||||||||:||..:..||...||.||..|.::|...:||.|.
  Rat   237 ---YCRLGEIRGHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGVTKFMQEVYLDKFIRLLDA 298

  Fly   385 PGLVF-PSSTPKSLQVLLGSFPISQLAVPYRSLKFLGEHLNLPQLLRLHLPEDYDEWSAVAISDA 448
            ||:|. |:|...:  :|.....:.:||.|...::.:.:..||         |:...:..|:   .
  Rat   299 PGIVAGPNSEVGT--ILRNCIHVQKLADPVTPVETILQRCNL---------EEISNYYGVS---G 349

  Fly   449 WAYKRGFLTAKAARPDRYR---------AANHILRMCLAGQQMLVLQFY---PPGFEERREHWL- 500
            :.....||||.|.|..:.:         ||..:|...::|:    :.||   ||      .|.|
  Rat   350 FQTTEHFLTAVAHRLGKKKKGGVYSQEQAAKAVLADWVSGK----ISFYTPPPP------THTLP 404

  Fly   501 QHPDVGEVKKYQQVELDEPESETNGDTSSVCSDTADSED 539
            .|.....||:..:|...|...:.|.||.. |....:|::
  Rat   405 THLSAEIVKEMTEVFDIEDTEQANEDTME-CLAVGESDE 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns4	NP_610055.1	HSR1_MMR1	163..390	CDD:206750	63/239 (26%)
		RbgA	204..474	CDD:440775	72/279 (26%)
Gnl3l	NP_001075427.1	DUF4670	<47..126	CDD:464815	22/104 (21%)
		Nucleostemin_like	129..301	CDD:206753	57/218 (26%)