DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fs(2)Ket and AT5G53480

DIOPT Version :9

Sequence 1:	NP_001246108.1	Gene:	Fs(2)Ket / 35336	FlyBaseID:	FBgn0262743	Length:	884	Species:	Drosophila melanogaster
Sequence 2:	NP_200160.1	Gene:	AT5G53480 / 835429	AraportID:	AT5G53480	Length:	870	Species:	Arabidopsis thaliana

Alignment Length:	897	Identity:	324/897 - (36%)
Similarity:	487/897 - (54%)	Gaps:	56/897 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IAMQLIAILEKTVSPDKNELLSAKNFLEQAAASNLPEFLKALSEILVNTANSAVARMAAGLQLKN 69
            :||::..:|....|.|......|:..|:|....||..||.:|:..|.|......:|..|||.|||
plant     1 MAMEVTQLLINAQSIDGTVRKHAEESLKQFQEQNLAGFLLSLAGELANDEKPVDSRKLAGLVLKN 65

  Fly    70 HLTSKDEKVSQQYQDRWHQFPSEIRELIKNNILAALG--TENTRPSCAAQCVAYVAVIELPINRW 132
            .|.:|::....:...||.......:..|:..:|..|.  ..:.| |.|:|.:|.||.||||..:|
plant    66 ALDAKEQHRKYELVQRWLALDMSTKSQIRAFLLKTLSAPVPDVR-STASQVIAKVAGIELPQKQW 129

  Fly   133 PMLIQTLVNKVVSEGSSEMH------RESALEAIGYICQDIRFGVMENQS-NDVLTAIIHGMRKV 190
            |.||.:|:        |.:|      :::.||.:||:|:::...|:|.:. |.:|||::.||...
plant   130 PELIVSLL--------SNIHQLPAHVKQATLETLGYLCEEVSPDVVEQEHVNKILTAVVQGMNAA 186

  Fly   191 EPSNHVRLAATTALHNSLEFTKSNFEKDMERNFIMEVVCEATQCQDSQICVAALQCLVKIMTLYY 255
            |.:..||||||.||:.:|.|.::||..||||::||.||||||...:.:|..||.:|||.|.:.||
plant   187 EGNTDVRLAATRALYMALGFAQANFNNDMERDYIMRVVCEATLSPEVKIRQAAFECLVSIASTYY 251

  Fly   256 QYMEPYMAQALFPITLAAMKSDNDAVALQGIEFWSNVCDEEIDLAIE-SQEATDQGRAPQRVSKH 319
            :.:..|| |.:|.||..|::.|:::||||.|||||::||||||:..| ..|.......|   ..:
plant   252 EKLAHYM-QDIFNITAKAVREDDESVALQAIEFWSSICDEEIDILEEYGGEFAGDSDVP---CFY 312

  Fly   320 YARGALQFLTPVLVEKLTKQDECD--DEDTWSPAKAASVCLMVLATCCEDEIVPHVLPFIKENIE 382
            :.:.||..|.|:|:|.|.||:|..  ||..|:.|.|...||.::|....|:|||||:|||:|.|.
plant   313 FTKQALPGLVPLLLETLLKQEEDQDLDEGAWNIAMAGGTCLGLVARAVGDDIVPHVMPFIEEKIS 377

  Fly   383 SPNWRFRDAAVMTFGSVLNGLETNTLKPLVEQAMPTLIR-LMYDSSVIVRDTIAWTFGRICDI-- 444
            .|:||.|:||...|||:|.|...:.|..:|..|:..::. |..|.|..|:||.|||.|||.:.
plant   378 KPDWREREAATYAFGSILEGPSADKLMAIVNAALTFMLNALTNDPSNHVKDTTAWTLGRIFEFLH 442

  Fly   445 ---IPEAAINETYLQTLLECFVKSLKSEPRVAANVCWAFIGLSDAAWEAAVTNDGETPETYALSP 506
               |....||:...|.::...::|:...|.||...|.|...|:....:...::        .|:|
plant   443 GSTIETPIINQANCQQIITVLIQSMNDAPNVAEKACGALYFLAQGYEDIGPSS--------PLTP 499

  Fly   507 YFEYIITQLLETTDRSDGAQANLRCAAYQALMDMIKNSPLDCYLVVQRTTLVILERLNQVMQMET 571
            :|:.||..||....|.|..::.||.|||:||.::::.|..:...:|.:...||:..|:..::.|.
plant   500 FFQEIIKSLLAVAHREDATESRLRTAAYEALNEVVRCSTDETSTMVLQLVPVIMMELHNTLEGEK 564

  Fly   572 QINNHSDRHQFNDLQSLLCATLQSVLRKVHEQDAP----QISDAIMTALLTMFNSSAGKSGVVQE 632
            .  :..:|.:.|:||.|||..||.:::|:..:...    :.:|.:|...|.:|..   :|....|
plant   565 L--SLDEREKQNELQGLLCGCLQVIIQKLGSEPTKSKFMEYADQMMGLFLRVFGC---RSATAHE 624

  Fly   633 EAFLAVSTLVELLGAQFAKYMPAFKDFLVMGLKNFQEYQVCCAAVGLTGDIFRALKDLMVPYSNE 697
            ||.||:..|....|..||||||.|..:|.|||:||:|||||...||:.||:.|||:|.::||.:.
plant   625 EAMLAIGALAYAAGPNFAKYMPEFYKYLEMGLQNFEEYQVCAVTVGVVGDVCRALEDKILPYCDG 689

  Fly   698 IMTVLINNLTEPTIHRTVKPQVLSAFGDIALSIGNHFLPYLSMVLDMLRVASNLQTDANNFD--M 760
            |||.|:.:|:...:||:|||.:.|.||||||:||..|..|....:.||:.|:.|...:...|  |
plant   690 IMTQLLKDLSSNQLHRSVKPPIFSCFGDIALAIGEDFDKYWRYSMPMLQSAAELSAHSAGADDEM 754

  Fly   761 NEYINELRESILEAYTGIIQGLKGVDQTAHTDVMHMEPHLMHIISFIKRIAQEGDVSDSMLASAA 825
            .||.|.||..|||||:||.||.|   .:|.|.:  :.|...||:.|:..|..|.|:.:.::.:|.
plant   755 TEYTNSLRNGILEAYSGIFQGFK---NSAKTQL--LIPFAPHILQFLDSIYMEKDMDEVVMKTAI 814

  Fly   826 GFIGDLCTSFGPRLYPLLDDAIIT-QFLAEGKRSKAQRTKMLCTWAVKEIKK 876
            |.:|||..:.|..:..|:..::.: :||.|...|:....|....||...|.:
plant   815 GVLGDLADTLGSHVGGLIQQSVSSKEFLNECLSSEDHTIKEAAEWAKHAITR 866

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fs(2)Ket	NP_001246108.1	KAP95	17..876	CDD:227540	321/883 (36%)
		IBN_N	27..107	CDD:281761	24/81 (30%)
		HEAT repeat	136..162	CDD:293787	6/31 (19%)
		HEAT repeat	179..209	CDD:293787	14/29 (48%)
		HEAT repeat	223..255	CDD:293787	15/31 (48%)
		HEAT repeat	264..291	CDD:293787	14/26 (54%)
		HEAT repeat	330..360	CDD:293787	14/31 (45%)
		HEAT repeat	373..401	CDD:293787	15/27 (56%)
		HEAT_EZ	386..441	CDD:290247	23/55 (42%)
		HEAT repeat	414..444	CDD:293787	13/30 (43%)
		HEAT repeat	457..482	CDD:293787	6/24 (25%)
		HEAT repeat	508..540	CDD:293787	14/31 (45%)
AT5G53480	NP_200160.1	KAP95	2..870	CDD:227540	324/896 (36%)
		HEAT repeat	132..160	CDD:293787	9/35 (26%)
		HEAT repeat	174..210	CDD:293787	16/35 (46%)
		HEAT repeat	219..245	CDD:293787	13/25 (52%)
		HEAT repeat	258..287	CDD:293787	16/29 (55%)
		HEAT repeat	368..396	CDD:293787	15/27 (56%)
		HEAT repeat	409..440	CDD:293787	13/30 (43%)
		HEAT repeat	458..483	CDD:293787	6/24 (25%)
		HEAT repeat	501..533	CDD:293787	14/31 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	238	1.000	Domainoid score	I597
eggNOG	1	0.900	-	-		E1_COG5215
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1707
Inparanoid	1	1.050	526	1.000	Inparanoid score	I287
OMA	1	1.010	-	-		QHG56400
OrthoDB	1	1.010	-	-		D769199at2759
OrthoFinder	1	1.000	-	-		FOG0003173
OrthoInspector	1	1.000	-	-		otm2657
orthoMCL	1	0.900	-	-		OOG6_101642
Panther	1	1.100	-	-	LDO	PTHR10527
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2136
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840