DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fs(2)Ket and AT3G08947

DIOPT Version :9

Sequence 1:	NP_001246108.1	Gene:	Fs(2)Ket / 35336	FlyBaseID:	FBgn0262743	Length:	884	Species:	Drosophila melanogaster
Sequence 2:	NP_001154598.2	Gene:	AT3G08947 / 3768765	AraportID:	AT3G08947	Length:	657	Species:	Arabidopsis thaliana

Alignment Length:	675	Identity:	240/675 - (35%)
Similarity:	377/675 - (55%)	Gaps:	38/675 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 MERNFIMEVVCEATQCQDSQICVAALQCLVKIMTLYYQYMEPYMAQALFPITLAAMKSDNDAVAL 283
            ||||:||::|||....::::|..||.:|||.|.:.||:.:|.|: |.||.:|..|:|.|.::|:|
plant     1 MERNYIMKMVCETACSKEAEIRQAAFECLVSIASTYYEVLEHYI-QTLFELTSNAVKGDEESVSL 64

  Fly   284 QGIEFWSNVCDEEIDLAIESQEATDQGRAPQRVSKHYARGALQFLTPVLVEKLTKQ--DECDDED 346
            |.|||||::||||||.......|:.....|.   ..:...||..|..:|:|.|.||  |:..|:|
plant    65 QAIEFWSSICDEEIDRQEYDSPASGDSSPPH---SSFIEKALPHLVQMLLETLLKQEEDQDHDDD 126

  Fly   347 TWSPAKAASVCLMVLATCCEDEIVPHVLPFIKENIESPNWRFRDAAVMTFGSVLNGLETNTLKPL 411
            .|:.:.|...||.::|....|.:||.|:||:::||.||:||.|:||...|||:|.|...:.|.|:
plant   127 VWNISMAGGTCLGLVARTVGDHVVPLVMPFVEKNISSPDWRCREAATYAFGSILEGPTIDKLAPM 191

  Fly   412 VEQAMPTLIRLMYDSSVIVRDTIAWTFGRICDII--PE---AAINETYLQTLLECFVKSLKSEPR 471
            |...:..|:....|.:..||||.|||..||.:.:  |:   :.|:...|..::...::|:|..|.
plant   192 VAAGLEFLLNATKDQNNHVRDTTAWTLSRIFEFLHSPDSGFSVISPENLPRIVSVLLESIKDVPN 256

  Fly   472 VAANVCWAFIGLSDAAWEAAVTNDGETPETYALSPYFEYIITQLLETTDRSDGAQANLRCAAYQA 536
            ||..||.|...|:....::..::.       .||||...|||.||...:|:|||::.||.|||:.
plant   257 VAEKVCGAIYNLAQGYEDSGASSS-------LLSPYLTEIITHLLAAAERTDGAESKLRGAAYET 314

  Fly   537 LMDMIKNSPL-DCYLVVQRTTLVILERLNQVMQMETQINNHSDRHQFNDLQSLLCATLQSVLRKV 600
            |.::::.|.| :...::......|:::|.:.|.:  .|.:..||.:..::|:.||..||.:::|:
plant   315 LNEVVRCSNLSEASSIIAHLLPAIMKKLAETMDL--PIISTDDREKQAEVQASLCGVLQVIIQKL 377

  Fly   601 --HEQDAP---QISDAIMTALLTMFNSSAGKSGVVQEEAFLAVSTLVELLGAQFAKYMPAFKDFL 660
              .|...|   |.:|.||...|.:|..   .|..|.|||.||:..|....||:|.||||....:|
plant   378 SGREDTKPIIMQSADDIMRLFLRVFGC---HSSSVHEEAMLAIGALAYATGAEFVKYMPELFKYL 439

  Fly   661 VMGLKNFQEYQVCCAAVGLTGDIFRALKDLMVPYSNEIMTVLINNLTEPTIHRTVKPQVLSAFGD 725
            .|||:||:|||||...||:.|||.|||.:.::|:.::||.:||.||....:||:|||.:.|.|||
plant   440 QMGLQNFEEYQVCSITVGVLGDICRALDEKILPFCDQIMGLLIQNLQSGALHRSVKPPIFSCFGD 504

  Fly   726 IALSIGNHFLPYLSMVLDMLRVASNL--QTDANNFDMNEYINELRESILEAYTGIIQGLKGVDQT 788
            |||:||.||..|::..:.:::.|:.:  |.|..:.::.:|.|:||.||.|||:||:||.|
plant   505 IALAIGAHFERYVAPAVQIMQGAAQVCAQMDTLDEELMDYANQLRRSIFEAYSGILQGFK----- 564

  Fly   789 AHTDVMHMEPHLMHIISFIKRIAQEGDVSDSMLASAAGFIGDLCTSFGPRLYPLLDD-AIITQFL 852
             .|....|.|:..|::.|::.::::....:|:..:|...:|||....|.....|..: ....:||
plant   565 -DTKAELMMPYAQHLLQFVELVSKDPLRDESVTKAAVAAMGDLADVVGENTKQLFQNFTFFGEFL 628

  Fly   853 AEGKRSKAQRTKMLCTWAVKEIKKI 877
            .|...|:.:..|:...|....|.::
plant   629 NECLESEDEDLKVTARWTQGMIARL 653

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fs(2)Ket	NP_001246108.1	KAP95	17..876	CDD:227540	240/672 (36%)
		IBN_N	27..107	CDD:281761
		HEAT repeat	136..162	CDD:293787
		HEAT repeat	179..209	CDD:293787
		HEAT repeat	223..255	CDD:293787	12/31 (39%)
		HEAT repeat	264..291	CDD:293787	14/26 (54%)
		HEAT repeat	330..360	CDD:293787	12/31 (39%)
		HEAT repeat	373..401	CDD:293787	15/27 (56%)
		HEAT_EZ	386..441	CDD:290247	22/54 (41%)
		HEAT repeat	414..444	CDD:293787	11/29 (38%)
		HEAT repeat	457..482	CDD:293787	8/24 (33%)
		HEAT repeat	508..540	CDD:293787	15/31 (48%)
AT3G08947	NP_001154598.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	238	1.000	Domainoid score	I597
eggNOG	1	0.900	-	-		E1_COG5215
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	526	1.000	Inparanoid score	I287
OMA	1	1.010	-	-		QHG56400
OrthoDB	1	1.010	-	-		D769199at2759
OrthoFinder	1	1.000	-	-		FOG0003173
OrthoInspector	1	1.000	-	-		otm2657
orthoMCL	1	0.900	-	-		OOG6_101642
Panther	1	1.100	-	-	O	PTHR10527
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2136
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840