DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fs(2)Ket and AT3G08943

DIOPT Version :9

Sequence 1:	NP_001246108.1	Gene:	Fs(2)Ket / 35336	FlyBaseID:	FBgn0262743	Length:	884	Species:	Drosophila melanogaster
Sequence 2:	NP_001154597.2	Gene:	AT3G08943 / 3768764	AraportID:	AT3G08943	Length:	871	Species:	Arabidopsis thaliana

Alignment Length:	891	Identity:	319/891 - (35%)
Similarity:	502/891 - (56%)	Gaps:	40/891 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IAMQLIAILEKTVSPDKNELLSAKNFLEQAAASNLPEFLKALSEILVNTANSAVARMAAGLQLKN 69
            :||::...|....|.|......|:..|.|....|||.||.:||..|.|....|.:|..||:.|||
plant     1 MAMEITQFLLAAQSADARVRTEAEASLRQFQEQNLPLFLLSLSFELENNDKPAESRRLAGILLKN 65

  Fly    70 HLTSKDEKVSQQYQDRWHQFPSEIRELIKNNILAALGTENTRP-SCAAQCVAYVAVIELPINRWP 133
            .|.:||.........:|......::..||:.:|..||:..... ..:||.:|.||.||:|..:||
plant    66 SLDAKDSATKDHLVKQWFAIDVALKSQIKDRLLRTLGSSALEARHTSAQVIAKVASIEIPQKQWP 130

  Fly   134 MLIQTLVNKVVSEGSSEMHRESALEAIGYICQDI-RFGVMENQSNDVLTAIIHGMRKVEPSNHVR 197
            .|:.:|:|.:..:||....::|.||.:||:|::| ...:::::.|.||||::.||.:.|.:..||
plant   131 ELVGSLLNNMTQQGSPAHLKQSTLETLGYVCEEISHHDLVQDEVNSVLTAVVQGMNQSENTAEVR 195

  Fly   198 LAATTALHNSLEFTKSNFEKDMERNFIMEVVCEATQCQDSQICVAALQCLVKIMTLYYQYMEPYM 262
            ||||.||.|:|:|:::|||.:||||:||::|||....::::|..||.:|||.|.:.||:.:|.|:
plant   196 LAATKALLNALDFSQTNFENEMERNYIMKMVCETACSKEAEIRQAAFECLVSIASTYYEVLEHYI 260

  Fly   263 AQALFPITLAAMKSDNDAVALQGIEFWSNVCDEEIDLAIESQEATDQGRAPQRVSKHYARGALQF 327
             |.||.:|..|:|.|.::||||.|||||::||||||.  :..::.|.|.:....| .:...||..
plant   261 -QTLFELTSNAVKGDEESVALQAIEFWSSICDEEIDR--QEYDSPDSGDSSPPHS-CFIEKALPH 321

  Fly   328 LTPVLVEKLTKQ--DECDDEDTWSPAKAASVCLMVLATCCEDEIVPHVLPFIKENIESPNWRFRD 390
            |..:|:|.|.||  |:..|:|.|:.:.|...||.::|....|.:||.|:||:::||.||:||.|:
plant   322 LVQMLLETLLKQEEDQDHDDDVWNISMAGGTCLGLVARTVGDGVVPLVMPFVEKNISSPDWRSRE 386

  Fly   391 AAVMTFGSVLNGLETNTLKPLVEQAMPTLIRLMYDSSVIVRDTIAWTFGRICDII--PE---AAI 450
            ||...|||:|.|...:.|.|:|...:..|:....|.:..||||.|||..||.:.:  |:   :.|
plant   387 AATYAFGSILEGPTIDKLAPMVAAGLEFLLNATKDQNNHVRDTTAWTLSRIFEFLHXPDSGFSVI 451

  Fly   451 NETYLQTLLECFVKSLKSEPRVAANVCWAFIGLSDAAWEAAVTNDGETPETYALSPYFEYIITQL 515
            :...|..::...::|:|..|.||..||.|...|:....::..::.       .||||...|||.|
plant   452 SPENLPRIVSVLLESIKDVPNVAEKVCGAIYNLAQGYEDSGASSS-------LLSPYLTEIITHL 509

  Fly   516 LETTDRSDGAQANLRCAAYQALMDMIKNSPL-DCYLVVQRTTLVILERLNQVMQMETQINNHSDR 579
            |...:|:|||::.||.|||:.|.::::.|.| :...::......|:::|.:.|.:  .|.:..||
plant   510 LAAAERTDGAESKLRGAAYETLNEVVRCSNLSEASSIIAHLLPAIMKKLAETMDL--PIISTDDR 572

  Fly   580 HQFNDLQSLLCATLQSVLRKVHEQD-----APQISDAIMTALLTMFNSSAGKSGVVQEEAFLAVS 639
            .:..:||:.||..||.:::|:..:|     ..|.:|.||...|.:|..   .|..|.|||.||:.
plant   573 EKQAELQASLCGVLQVIIQKLSSRDDMKPIIVQNADDIMRLFLRVFGC---HSSSVHEEAMLAIG 634

  Fly   640 TLVELLGAQFAKYMPAFKDFLVMGLKNFQEYQVCCAAVGLTGDIFRALKDLMVPYSNEIMTVLIN 704
            .|....|.:|.||||....:|.|||:||:|||||...||:.|||.|||.:.::|:.::||.:||.
plant   635 ALAYATGTEFVKYMPELFKYLQMGLQNFEEYQVCSITVGVIGDICRALDEKILPFCDQIMGLLIQ 699

  Fly   705 NLTEPTIHRTVKPQVLSAFGDIALSIGNHFLPYLSMVLDMLRVASNL--QTDANNFDMNEYINEL 767
            ||....:||:|||.:.|.||||||:||.||..|::..:.:::.|:.:  |.|..:.::.:|.|:|
plant   700 NLQSGALHRSVKPPIFSCFGDIALAIGAHFERYVAPAVQIMQGAAQVCAQMDTLDEELMDYANQL 764

  Fly   768 RESILEAYTGIIQGLKGVDQTAHTDVMHMEPHLMHIISFIKRIAQEGDVSDSMLASAAGFIGDLC 832
            |.||.|||:||:||.|  |..|..    |.|:..|::.|::.::::....:|:..:|...:|||.
plant   765 RRSIFEAYSGILQGFK--DAKAEL----MMPYAQHLLQFVELVSKDSLRDESVTKAAVAAMGDLA 823

  Fly   833 TSFGPRLYPLLDD-AIITQFLAEGKRSKAQRTKMLCTWAVKEIKKI 877
            ...|.....|..: ....:||.|...|:.:..|:...|....|.::
plant   824 DVVGENTKQLFQNFTFCDEFLNECLESEDEDLKVTARWTQGMIARL 869

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fs(2)Ket	NP_001246108.1	KAP95	17..876	CDD:227540	316/876 (36%)
		IBN_N	27..107	CDD:281761	27/79 (34%)
		HEAT repeat	136..162	CDD:293787	7/25 (28%)
		HEAT repeat	179..209	CDD:293787	16/29 (55%)
		HEAT repeat	223..255	CDD:293787	12/31 (39%)
		HEAT repeat	264..291	CDD:293787	15/26 (58%)
		HEAT repeat	330..360	CDD:293787	12/31 (39%)
		HEAT repeat	373..401	CDD:293787	15/27 (56%)
		HEAT_EZ	386..441	CDD:290247	22/54 (41%)
		HEAT repeat	414..444	CDD:293787	11/29 (38%)
		HEAT repeat	457..482	CDD:293787	8/24 (33%)
		HEAT repeat	508..540	CDD:293787	15/31 (48%)
AT3G08943	NP_001154597.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	238	1.000	Domainoid score	I597
eggNOG	1	0.900	-	-		E1_COG5215
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	526	1.000	Inparanoid score	I287
OMA	1	1.010	-	-		QHG56400
OrthoDB	1	1.010	-	-		D769199at2759
OrthoFinder	1	1.000	-	-		FOG0003173
OrthoInspector	1	1.000	-	-		otm2657
orthoMCL	1	0.900	-	-		OOG6_101642
Panther	1	1.100	-	-	O	PTHR10527
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2136
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840