Protein Alignment TM9SF2 and Tm9sf4

DIOPT Version :9

• Sequence 1: NP_001260637.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: XP_006500539.1
• Gene: Tm9sf4 / 99237
• MGIID: 2139220
• Length: 644
• Species: Mus musculus
• Alignment Length: 658
• Identity: 285/658 - (43%)
• Similarity: 414/658 - (62%)
• Gaps: 37/658 - (5%)

  Fly    13 VVLLHLATPTQAFYLPGLAPVNFCKKTDVSSTCKSEILLYVNRLNTEESVIPYEYHHFDFCLGEE 77
            ::||.|......||:||:||:||.:...|.        :...:|.:..:.:||||:...||...:
Mouse    13 LLLLCLTCKGSTFYVPGVAPINFHQNDPVE--------IKAVKLTSSRTQLPYEYYSLPFCQPIK 69

  Fly    78 QNSPVENLGQVVFGERIRPGPYKIQFLENQQCATTCVKTYKGDDPASNRRMMVLKKGISLNYQHH 142
            .....||||:|:.|:||...|:::.....::|...|.::.|.......:..:|.:: |:..|..|
Mouse    70 ITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCNQSNKPITLTVEQSRLVAER-ITEEYYVH 133

  Fly   143 WIVDNMPVTWCYPL-------ENGKQYCGIGFPMGC-LVRSDGEGCPINSIYNQPMHYYPFNHVD 199
            .|.||:||.....|       ::.|:...:.|..|. |..:|     :|.||   :|    ||:.
Mouse   134 LIADNLPVATRLELYSSNRDSDDKKKEKDVQFEHGYRLGFTD-----VNKIY---LH----NHLS 186

  Fly   200 LEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKHTD---KENPNCLSTEPLAISENSLKAGEQL 261
            ..:.||   .||......::.|::..:|.|:||:..|   .|..:|...|........:...::.
Mouse   187 FILYYH---REDMEEDQEHTYRVVRFEVIPQSIRLEDLKTGEKSSCTLPEGANSLPQEIDPTKEN 248

  Fly   262 EIVYTYSVKFVKNDSIKWSSRWDYILESMPHTNIQWFSILNSLVIVLFLSGMVAMIMLRTLHKDI 326
            ::.:||||.:.::| |||:||||..| :|....|.||||:||:|:|.||||:::||::|||.|||
Mouse   249 QLYFTYSVHWEESD-IKWASRWDTYL-TMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDI 311

  Fly   327 ARYNQMDSGEDAQEEFGWKLVHGDVFRPPRKGMLLSVFLGSGVQVLVMAMITLAFACLGFLSPAN 391
            |.||:.|..||..||.|||||||||||||:..|:||..||||:|:..|.:|.:..|.||.|||::
Mouse   312 ANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSS 376

  Fly   392 RGALMTCSMVLFVSLGTPAGYVSARIYKSFGGLKWKSNVILTSIVCPGVVFSLFFVMNLVLWGEN 456
            ||||||.:..||:.:|...|:.:.|:|::..|.:||.....|:.:.|||||.:.||:|..:||::
Mouse   377 RGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKH 441

  Fly   457 SSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFRKRALEHPVRTNQIPRQIPDQSIYTQPIPGIV 521
            |||||||.|::|||.:|||:|:||.::|.||||||:..::||||||||||||:|..|.....||:
Mouse   442 SSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGIL 506

  Fly   522 MGGVLPFGCIFIQLFFILSSLWSSQIYYMFGFLFLVFVILVITCSETTILLCYFHLCAEDYHWWW 586
            |.|:||||.:||:||||.|::|.:|.||:||||||||:|||::||:.:|::.||.||||||.|||
Mouse   507 MAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWW 571

  Fly   587 RSFLTSGFTAVYLFIYCCHYFVTKLSIKDSASTFLYFGYTAIMVFLFFLLTGTIGFFACFWFIRK 651
            |:||.||.:|.|:.:|...|||.||.|.:...:.||||||.:||..|:||||||||:|.:.|:||
Mouse   572 RNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTTLMVLSFWLLTGTIGFYAAYMFVRK 636

  Fly   652 IYSVVKVD 659
            ||:.||:|
Mouse   637 IYAAVKID 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_001260637.1	EMP70	64..613	CDD:397233	245/559 (44%)
Tm9sf4	XP_006500539.1	EMP70	56..601	CDD:367285	246/562 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000597
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100462
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1983
SonicParanoid	1	1.000	-	-		X358
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.750