Protein Alignment TM9SF2 and TMN3

DIOPT Version :9

• Sequence 1: NP_001260637.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_011038.3
• Gene: TMN3 / 856849
• SGDID: S000000915
• Length: 706
• Species: Saccharomyces cerevisiae
• Alignment Length: 759
• Identity: 185/759 - (24%)
• Similarity: 320/759 - (42%)
• Gaps: 179/759 - (23%)

  Fly     7 LLPLLGVVLLHLATPTQAFYLP-----GLAPV---------------NFCKKTDVSSTCKSEILL 51
            ::.|:.:|::.|....| ||..     |..||               ||.:|.|       .:.|
Yeast     9 VITLMAIVVVMLILRNQ-FYSSRTRGHGQEPVISSSQKNLYDGWITPNFYRKGD-------PLEL 65

  Fly    52 YVNRLNTEESVIPYEYHHFDF-CLGEEQNSPVE-NLGQVVFGERIRPGPYKIQFLENQQCATTCV 114
            .||::.::.:.:||.|:...| |.......|:. :|.:::.|:|.....||::|.|:..|.|.|.
Yeast    66 IVNKVESDLTQLPYAYYDLPFTCPPTMHKKPLHLSLNEIIRGDRKWESDYKLKFGEDNPCETLCA 130

  Fly   115 -KTYKGDDPASNRRMMVLKKGISLNYQHHWIVDN-MP-VTWCYPLENGKQYCGIGFPMGCLVRSD 176
             ||.|       ..|..|.|.:...|...|::|: :| .|......:.|:|...|||:| .:..|
Yeast   131 RKTTK-------EGMQTLDKLVREGYVVQWLIDDELPAATTFISTTDHKKYYASGFPLG-FIDPD 187

  Fly   177 GEGCPINSIYNQPMHYYPFNHVDLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKHTDKENPN 241
            .:            ..|..|||.|.|.:|:..::        ...|:..:|.|:|:  :|...|.
Yeast   188 TD------------KTYLHNHVMLVIRFHASDND--------KNTIVGFEVYPRSV--SDYHCPG 230

  Fly   242 CLSTEPLAISENSLKAGEQLEIV------------YTYSVKFVKNDSIKWSSRWDYIL---ESMP 291
            .        |:|.    ||.|||            :||||.:.:...:.|:.||||.|   |...
Yeast   231 A--------SKNY----EQYEIVIPEDENELTYLPFTYSVYWREEFEVDWNHRWDYFLNAGELSD 283

  Fly   292 HTNIQ--WFSILNSLVIVLFLSGMVAMIMLRTLHKD---------IARYNQMDSGEDAQEE-FG- 343
            ..:||  |.|:.||:.|||.:|.:..:|.:|.::.|         :.....:::.:|..:: :|
Yeast   284 EQSIQFHWMSLANSVGIVLSISFITLIIYVRVMYTDKSNSKSPKYMINIEGIETEDDLDDDKYGK 348

  Fly   344 ---------WKLVHGDVFRPPRKGMLLSVFLGS-GVQVLVMAMITLAFACLGFLSPANRGALMTC 398
                     | :.:|   ||...|:.:.:.|.| |||.|...:.:|..:|........|.:::|.
Yeast   349 YSVYTVAKDW-IQNG---RPNLFGLKVLILLVSFGVQFLFTIIGSLTISCSMNKLHNVRNSVLTM 409

  Fly   399 SMVLFVSLGTPAGYVSARIYKSFGGLKWKSNVI--------------LTSIVC----PGVVFSLF 445
            :::.||.....|.:|..|:.......:.|:|.:              :.:|:|    ||:|....
Yeast   410 AILFFVLGAFMASFVGTRLSMVTKTKRTKANYLDDNRYLKDYKKFSPIFTILCGSSLPGIVMVST 474

  Fly   446 FVMNLVLWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFRKRALEHPVRTNQIPRQ---- 506
            |::|.::|..:|:.|:||.|::..::::|.|.:||:..|.            :..|.||..
Yeast   475 FLLNSIVWAHDSTSALPFKTIVFFMSIYFIVCIPLSLFGG------------IVANNIPLPQYWL 527

  Fly   507 ----------------IPDQSIYTQPIP--GIVMGGVLPFGCIFIQLFFILSSLW--SSQIYYMF 551
                            :|.......|:.  ||.:.|:.|...|::::.::..|||  .:..||.:
Yeast   528 SGITKDESNSDGNGLFVPKSRAKFNPLVYCGIYLCGIFPLLVIYVEMQYVYKSLWLEKTTFYYFY 592

  Fly   552 GFLFLVFVILVITCSETTILLCY--FHLCAED----YHWWWRSFLTSGFT-AVYLFIYCCHYFVT 609
            |||||..::|.:...|.:|:..|  ...|.||    .:|.|:.| ..||: .||:.:|..:|...
Yeast   593 GFLFLSIILLCVLTMEISIIGSYLLMRFCFEDKVVRNNWRWKCF-EMGFSGGVYMELYSLYYIFA 656

  Fly   610 KLSIKDSASTFLYFGYTAIMVFLFFLLTGTIGFFACFWFIRKIY 653
            .|:|...:|..:...|:.|...:..|..|.:.:....|||.|||
Yeast   657 VLNIHGFSSILISICYSLIFNVMCSLGLGALSYLTASWFINKIY 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_001260637.1	EMP70	64..613	CDD:397233	157/640 (25%)
TMN3	NP_011038.3	EMP70	78..663	CDD:397233	158/643 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10766
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880