DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TM9SF2 and AT2G01970

DIOPT Version :9

Sequence 1:	NP_001260637.1	Gene:	TM9SF2 / 35335	FlyBaseID:	FBgn0032880	Length:	659	Species:	Drosophila melanogaster
Sequence 2:	NP_178306.1	Gene:	AT2G01970 / 814728	AraportID:	AT2G01970	Length:	592	Species:	Arabidopsis thaliana

Alignment Length:	617	Identity:	195/617 - (31%)
Similarity:	306/617 - (49%)	Gaps:	71/617 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 LYVNRL----NTEESVIPYEYHHFDFCLGEEQNSPVENLGQVVFGERIRPGPYKIQFLENQQCAT 111
            ||.|::    |..|:   |.|....||:.|......|.||:|:.|:|:...|||:.|.:.:....
plant    39 LYANKVGPFHNPSET---YRYFDLPFCIPEGVKDKKEALGEVLNGDRLVSAPYKLNFRDEKDSEV 100

  Fly   112 TCVKTYKGDDPASNRRMMVLKKGISLNYQHHWIVDNMPVTWCYPLENGKQYCGIGFPMGCLVRSD 176
            .|.|....::....||      .:..:|......|::|: |                 |.:.:.|
plant   101 YCKKKLSREEVEHFRR------AVEKDYYFQMYYDDLPI-W-----------------GFIGKVD 141

  Fly   177 GEGCPINSIYNQPMHYYPFNHVDLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKHTDKENPN 241
            .|.....|.:.    |:.:.|:..||.|             |..|:|.:..         :.:|:
plant   142 KESKSDPSEFK----YFLYKHIQFEILY-------------NKDRVIEINA---------RMDPH 180

  Fly   242 CLSTEPLAISENSLKAGEQLEIVYTYSVKFVKNDSIKWSSRWD-YIL-ESMP-HTNIQWFSILNS 303
            .|.         .|...::::..:.|:||: |.....:..|.| |.: .|:| |..|.||||:||
plant   181 SLV---------DLTEDKEVDAEFMYTVKW-KETETSFEKRMDKYAMSSSLPHHLEIHWFSIINS 235

  Fly   304 LVIVLFLSGMVAMIMLRTLHKDIARYNQMDSGEDAQEEFGWKLVHGDVFRPPRKGMLLSVFLGSG 368
            .|.||.|:|.:|.|::|.|..|..:|.|.:...|.|||.|||.:||||||.|:...|.:..||||
plant   236 CVTVLLLTGFLATILMRVLKNDFMKYAQDEEAADDQEETGWKYIHGDVFRFPKNKSLFAASLGSG 300

  Fly   369 VQVLVMAMITLAFACLGFLSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGGLKWKSNVILT 433
            .|:..:.:.....:.:|...|.|||||.|..:|::......|||.::..|....|..|..|::||
plant   301 TQLFTLTIFIFMLSLVGVFYPYNRGALFTALVVIYALTSGIAGYTASSFYCQLEGKNWVRNLLLT 365

  Fly   434 SIVCPGVVFSLFFVMNLVLWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFRKRA-LEHP 497
            ..:..|.:|..|..:|.|....:::.|:||.|:|.::.:|..|:.||..:|...|...:| .:.|
plant   366 GGLFCGPLFLTFCFLNTVAIAYSATAALPFGTIIVIVLIWTLVTSPLLVLGGIAGKNSKAEFQAP 430

  Fly   498 VRTNQIPRQIPDQSIYTQPIPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYYMFGFLFLVFVILV 562
            |||.:.||:||....|...:|.:.|.|.|||..|:|:|::|.:|:|..:||.::..||:||:||:
plant   431 VRTTKYPREIPPLPWYRSAVPQMAMAGFLPFSAIYIELYYIFASVWGHRIYTIYSILFIVFIILL 495

  Fly   563 ITCSETTILLCYFHLCAEDYHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIKDSASTFLYFGYTA 627
            |..:..|:.|.||.|.|||:.|||||||..|.|.::::.||.:|:..:..:.....|..:|||.|
plant   496 IVTAFITVALTYFQLAAEDHEWWWRSFLCGGSTGLFIYAYCLYYYYARSDMSGFMQTSFFFGYMA 560

  Fly   628 IMVFLFFLLTGTIGFFACFWFIRKIYSVVKVD 659
            .:.:.|||:.||:||.|...|:|.||..:|.:
plant   561 CICYGFFLMLGTVGFRAALLFVRHIYRSIKCE 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_001260637.1	EMP70	64..613	CDD:397233	172/552 (31%)
AT2G01970	NP_178306.1	EMP70	54..549	CDD:397233	172/554 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D641127at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830