Protein Alignment TM9SF2 and Tm9sf1

DIOPT Version :9

• Sequence 1: NP_001260637.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_001346992.1
• Gene: Tm9sf1 / 74140
• MGIID: 1921390
• Length: 606
• Species: Mus musculus
• Alignment Length: 681
• Identity: 206/681 - (30%)
• Similarity: 333/681 - (48%)
• Gaps: 118/681 - (17%)

  Fly     8 LPLLGVVLLHLATPTQAFYLPGLAPVNFCKKTDVSSTCKSEILLYVNRL----NTEESVIPYEYH 68
            ||:| ::||.:.      :.|.:..|...|..|       .::||||::    |.:|:   |.|:
Mouse    15 LPVL-ILLLGIG------HGPWVEGVTHYKPGD-------PVILYVNKVGPYHNPQET---YHYY 62

  Fly    69 HFDFCLGEEQNSPVENLGQVVFGERIRPGPYKIQFLENQQCATTCVKTYKGDDPASNRRMMVLKK 133
            ....|..|:......:||:|:.|:|:....|:|:|.||.:....|      ....|:.::..|::
Mouse    63 QLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILC------HMQLSSAQVEQLRQ 121

  Fly   134 GISLNYQHHWIVDNMPVTWCYPLENGKQYCGIGFPMGCLVRSDGEGCPINSIYNQPMHYYPFNHV 198
            .|...|...::||::|:         :.:.|.....|.|..|...|.              :.|:
Mouse   122 AIEELYYFEFVVDDLPI---------RGFVGYMEESGFLPHSHKIGL--------------WTHL 163

  Fly   199 DLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKHTDKENPNCLSTEPLAISENSLKAGEQLEI 263
            |..:.:|             ..|||...|:.:.:|      |:.|         :.|::.|.|.:
Mouse   164 DFHLEFH-------------GDRIIFANVSVRDVK------PHSL---------DGLRSDELLGL 200

  Fly   264 VYTYSVKFVKNDSIKWSSRWDYILESMPHTN----------------IQWFSILNSLVIVLFLSG 312
            .:||||        :||.      .|:.|.:                |.|.||:||:|:|..|.|
Mouse   201 THTYSV--------RWSE------TSVEHRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVG 251

  Fly   313 MVAMIMLRTLHKDIARYN---QMDSGEDA----QEEFGWKLVHGDVFR-PPRKGMLLSVFLGSGV 369
            .||:|::|.|..|:||||   :..||..:    |.:.|||::|.|||| ||.:|:|.:| ||.|.
Mouse   252 FVAVILMRVLRNDLARYNLDEETSSGGSSDDFDQGDNGWKIIHTDVFRFPPYRGLLCAV-LGVGA 315

  Fly   370 QVLVMAMITLAFACLGFLSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGGLKWKSNVILTS 434
            |.|.:....:..|.||..:....||:.:.:::|:......:||||:..|:..||.:|..|:||||
Mouse   316 QFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTS 380

  Fly   435 IVCPGVVFSLFFVMNLVLWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFRKRA-LEHPV 498
            .:.....|..:.|:|.|.|...|:.|:|.:|::.||.:|..|..|||.:|..||....: .:.|.
Mouse   381 SLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNNASPFDAPC 445

  Fly   499 RTNQIPRQIPDQSIYTQPIPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYYMFGFLFLVFVILVI 563
            ||..|.|:||.|..|...:..:.:||.|||..|.::|::|.:::|..:.|.::|.||.||.||:.
Mouse   446 RTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISVELYYIFATVWGREQYTLYGILFFVFAILLS 510

  Fly   564 TCSETTILLCYFHLCAEDYHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIKDSASTFLYFGYTAI 628
            ..:..:|.|.||.|..|||.|||||.|:.|.|.:::|:|...|:..:.::..:..|..:|||:.:
Mouse   511 VGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLL 575

  Fly   629 MVFLFFLLTGTIGFFACFWFIRKIYSVVKVD 659
            ..::|||:.|||.||:...|||.||..:|:|
Mouse   576 TGYVFFLMLGTISFFSSLKFIRYIYVNLKMD 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_001260637.1	EMP70	64..613	CDD:397233	172/573 (30%)
Tm9sf1	NP_001346992.1	EMP70	59..562	CDD:367285	172/574 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D135708at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830