Protein Alignment TM9SF2 and Tm9sf2

DIOPT Version :10

• Sequence 1: NP_610053.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_542123.3
• Gene: Tm9sf2 / 68059
• MGIID: 1915309
• Length: 662
• Species: Mus musculus
• Alignment Length: 663
• Identity: 441/663 - (66%)
• Similarity: 530/663 - (79%)
• Gaps: 20/663 - (3%)

  Fly     1 MILLSGLLPLLGVVLLHLATPTQAFYLPGLAPVNFCKKTDVSSTCKSEILLYVNRLNTEESVIPY 65
            ::|||  |.|||.|  ....|..|||||||||||||.: :.|:.||::|.|:||||::.|||:||
Mouse    16 LLLLS--LLLLGTV--PGPRPGSAFYLPGLAPVNFCAE-EKSNECKADIELFVNRLDSVESVLPY 75

  Fly    66 EYHHFDFCLGEEQNSPVENLGQVVFGERIRPGPYKIQFLENQQCATTCVKTYKGDDPASNRRMMV 130
            ||..||||...|...|.||||||:|||||.|.|||..|.:.:.|...|.|||..:.....:::..
Mouse    76 EYTAFDFCQASEGKRPSENLGQVLFGERIEPSPYKFTFNKKETCKLVCTKTYNTEKAEDKQKLDF 140

  Fly   131 LKKGISLNYQHHWIVDNMPVTWCYPLENGKQYCGIGFPMGCLVRSDG---EGCPINSIYNQPMHY 192
            |||.:.||||||||||||||||||.:|:.:::|..|||:||.:...|   :.|.|:|.:::...:
Mouse   141 LKKSMLLNYQHHWIVDNMPVTWCYEVEDSQKFCNPGFPIGCYITDKGHAKDACVISSEFHERDTF 205

  Fly   193 YPFNHVDLEITYHSGQSEDWGIQFGNSG-RIISVKVTPKSIKHTDKENPNCLSTEPLAISENSLK 256
            |.|||||::|.||.       ::.|:.| |:::.|:.|||.|||..:.|:| |...:.||.   |
Mouse   206 YIFNHVDIKIYYHV-------VETGSMGARLVAAKLEPKSFKHTHIDKPDC-SGPAMDISN---K 259

  Fly   257 AGEQLEIVYTYSVKFVKNDSIKWSSRWDYILESMPHTNIQWFSILNSLVIVLFLSGMVAMIMLRT 321
            |..:::|.||||:.|.:..:|:|:|||||||||||||:||||||:||||||||||||||||||||
Mouse   260 ASGEIKIAYTYSISFEEEKNIRWASRWDYILESMPHTHIQWFSIMNSLVIVLFLSGMVAMIMLRT 324

  Fly   322 LHKDIARYNQMDSGEDAQEEFGWKLVHGDVFRPPRKGMLLSVFLGSGVQVLVMAMITLAFACLGF 386
            |||||||||||||.|||||||||||||||:|||||||||||||||||.|:|:|..:||.||||||
Mouse   325 LHKDIARYNQMDSTEDAQEEFGWKLVHGDIFRPPRKGMLLSVFLGSGTQILIMTFVTLFFACLGF 389

  Fly   387 LSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGGLKWKSNVILTSIVCPGVVFSLFFVMNLV 451
            ||||||||||||::||:|.||||||||:||.||||||.|||:||:|||.:|||:||:.||:|||:
Mouse   390 LSPANRGALMTCAVVLWVLLGTPAGYVAARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLI 454

  Fly   452 LWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFRKRALEHPVRTNQIPRQIPDQSIYTQP 516
            ||||.||.|:||.||:|:|||||.:||||||:||||||:|.|:||||||||||||||:||.||:|
Mouse   455 LWGEGSSAAIPFGTLVAILALWFCISVPLTFIGAYFGFKKNAIEHPVRTNQIPRQIPEQSFYTKP 519

  Fly   517 IPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYYMFGFLFLVFVILVITCSETTILLCYFHLCAED 581
            :|||:|||:||||||||||||||:|:||.|:|||||||||||:||||||||.|||||||||||||
Mouse   520 LPGIIMGGILPFGCIFIQLFFILNSIWSHQMYYMFGFLFLVFIILVITCSEATILLCYFHLCAED 584

  Fly   582 YHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIKDSASTFLYFGYTAIMVFLFFLLTGTIGFFACF 646
            |||.|||||||||||||..||..|||.:||.|..:|||.||||||.|||.:|||.||||||||||
Mouse   585 YHWQWRSFLTSGFTAVYFLIYAIHYFFSKLQITGTASTILYFGYTMIMVLIFFLFTGTIGFFACF 649

  Fly   647 WFIRKIYSVVKVD 659
            ||:.|||||||||
Mouse   650 WFVTKIYSVVKVD 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_610053.1	EMP70	64..613	CDD:460774	370/552 (67%)
Tm9sf2	NP_542123.3	EMP70	74..618	CDD:460774	371/554 (67%)