Protein Alignment TM9SF2 and TM9SF3

DIOPT Version :9

• Sequence 1: NP_001260637.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: XP_011538278.1
• Gene: TM9SF3 / 56889
• HGNCID: 21529
• Length: 607
• Species: Homo sapiens
• Alignment Length: 629
• Identity: 196/629 - (31%)
• Similarity: 317/629 - (50%)
• Gaps: 92/629 - (14%)

  Fly    46 KSEILLYVNRL----NTEESVIPYEYHHFDFCLGEEQNSP--VENLGQVVFGERIRPGPYKIQFL 104
            |.|::|::|.:    |.:|:   |:|....||:|.:::..  .|.||:.:.|..:......|:|.
Human    56 KEEVVLWMNTVGPYHNRQET---YKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFK 117

  Fly   105 ENQQCATTCVKTYKGDDPASNRRMMVLKKGISLNYQHHWIVDNMPVTWCYPLENGKQYCGIGFPM 169
            ::...||.|    :.|.....|...|.  .|..:|.:...:|::|: |
Human   118 DDVMPATYC----EIDLDKEKRDAFVY--AIKNHYWYQMYIDDLPI-W----------------- 158

  Fly   170 GCLVRSDGEGCPINSIYNQPMHYYPFNHVDLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKH 234
            |.:..:|..|          ..||.:.:..|||.:             |..||:.|.:|
Human   159 GIVGEADENG----------EDYYLWTYKKLEIGF-------------NGNRIVDVNLT------ 194

  Fly   235 TDKENPNCLSTEPLAISENSLKAGEQLEIVYTYSVKFVKNDSIKWSSRWD-YILESMPHTNIQWF 298
                            ||..:|.....:|..:||||:.|:| :|:..|:| |:..|.....|.||
Human   195 ----------------SEGKVKLVPNTKIQMSYSVKWKKSD-VKFEDRFDKYLDPSFFQHRIHWF 242

  Fly   299 SILNSLVIVLFLSGMVAMIMLRTLHKDIARYNQM----DSGEDAQEEFGWKLVHGDVFRPPRKGM 359
            ||.||.::|:||.|:|:||::|||.||.|||::.    |...|..:|:|||.||||||||....:
Human   243 SIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPL 307

  Fly   360 LLSVFLGSGVQVLVMAMITLAFACLGFLSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGGL 424
            :.|..:|||.|:..:::|.:..|.:..|. ..||::::.::.::.:.....||....:|...||.
Human   308 IFSSLIGSGCQIFAVSLIVIIVAMIEDLY-TERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGR 371

  Fly   425 KWKSNVILTSIVCPGVVFSLFFVMNLVLWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGF 489
            :|...:.:.:.:.|.:|....|.:|.:....::|.|:||.|::|:..:.|.|.:||..||...|
Human   372 RWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILG- 435

  Fly   490 RKRAL----EHPVRTNQIPRQIPDQSIYTQPIPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYYM 550
              |.|    ..|.|.|.:||.||::..:.:|...:.:||:||||.|||:::||.:|.|:.:|||:
Human   436 --RNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYV 498

  Fly   551 FGFLFLVFVILVITCSETTILLCYFHLCAEDYHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIKD 615
            :||:.||.|||.|.....||:..||.|.||||.|.|.|||::..||:|:::|..:|:..|..:..
Human   499 YGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYG 563

  Fly   616 SASTFLYFGYTAIMVFLFFLLTGTIGFFACFWFIRKIYSVVKVD 659
            ...|..||||.|:......::.|.||:.....|:||||:.||:|
Human   564 LFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_001260637.1	EMP70	64..613	CDD:397233	173/559 (31%)
TM9SF3	XP_011538278.1	EMP70	75..545	CDD:281048	168/546 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D135708at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.830