Protein Alignment TM9SF2 and tm9sf4

DIOPT Version :9

• Sequence 1: NP_001260637.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_956804.2
• Gene: tm9sf4 / 393482
• ZFINID: ZDB-GENE-040426-1575
• Length: 651
• Species: Danio rerio
• Alignment Length: 681
• Identity: 286/681 - (41%)
• Similarity: 410/681 - (60%)
• Gaps: 68/681 - (9%)

  Fly     2 ILLSGLLPLLGVVLLHLATPTQAFYLPGLAPVNFCKKTDVSSTCKSEILLYVNRLNTEESVIPYE 66
            :||...||.:.           .||:||:||:||.:.:.|.        :...:|.:..:.:|||
Zfish    16 LLLVSTLPCVA-----------PFYVPGVAPMNFHQNSPVE--------IKAVKLTSSRTQLPYE 61

  Fly    67 YHHFDFCLGEEQNSPVENLGQVVFGERIRPGPYKIQFLENQQCATTCVKTYKGDDPASNRRMMV- 130
            |:...||..|......||||:|:.|:||....|.:....:::|...|.|      |.|..::.|
Zfish    62 YYSLPFCKPENIVYKAENLGEVLRGDRIVNTLYTVFMNLDKKCEVLCKK------PESPIKLSVE 120

  Fly   131 ----LKKGISLNYQHHWIVDNMPVTWCYPLENGKQYC---------------GIGFPMGCLVRSD 176
                |.:.|...|..|.|.||:||.....|...|:..               ..|:.:|
Zfish   121 ESKLLAERIQEEYYIHLIADNLPVATRLELYPNKEEAIDEEQKKDTLKDVQFEHGYRLG------ 179

  Fly   177 GEGCPINSIYNQPMHYYPFNHVDLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKHTD---KE 238
                     :.:...:|..||:...:.:|..:.||   ...::.|::..:|.|||:|..|   .:
Zfish   180 ---------FTENNKFYLHNHLSFILYFHKEKLED---AEEHNYRVVRFEVMPKSVKLEDIKADD 232

  Fly   239 NPNCLSTEPLAISENSLKAGEQLEIVYTYSVKFVKNDSIKWSSRWDYILESMPHTNIQWFSILNS 303
            ...|...|.:|.....:...::..|::||||.:.::: :||:||||..| :|....|.||||:||
Zfish   233 RGTCTLPETVAPVPQEIDPSKENNILFTYSVHWQESE-VKWASRWDTYL-TMSDVQIHWFSIINS 295

  Fly   304 LVIVLFLSGMVAMIMLRTLHKDIARYNQMDSGEDAQEEFGWKLVHGDVFRPPRKGMLLSVFLGSG 368
            :|:|.||||:::||::|||.||||.||:.|..||..||.|||.|||||||||:..|:||..||||
Zfish   296 VVVVFFLSGILSMIIIRTLRKDIANYNREDDIEDTMEESGWKNVHGDVFRPPQYPMILSSLLGSG 360

  Fly   369 VQVLVMAMITLAFACLGFLSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGGLKWKSNVILT 433
            :|:..|.:|.:..|.||.|||::||||||.:..||:.:|...||.:.|:|::..|.:||.....|
Zfish   361 IQMFSMVLIVIFVAMLGMLSPSSRGALMTTACFLFMFMGLFGGYFAGRLYRTLKGHRWKKGAFCT 425

  Fly   434 SIVCPGVVFSLFFVMNLVLWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFRKRALEHPV 498
            :.:.|.|||.:.||:|..:|||:|||||||:|::|||.:|||:|:||.::|.||||||:..::||
Zfish   426 ATLYPAVVFGICFVLNCFIWGEHSSGAVPFTTMLALLCMWFGISLPLVYLGYYFGFRKQPYDNPV 490

  Fly   499 RTNQIPRQIPDQSIYTQPIPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYYMFGFLFLVFVILVI 563
            ||||||||:|:|..|.....||:|.|:||||.:||:||||.|::|.:|.||:||||||||:|||:
Zfish   491 RTNQIPRQVPEQRWYMNKFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVV 555

  Fly   564 TCSETTILLCYFHLCAEDYHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIKDSASTFLYFGYTAI 628
            :||:.:|::.||.||||||.||||:||.||.:|.|:.||...|||.||.|.:...:.|||||||:
Zfish   556 SCSQISIVMVYFQLCAEDYRWWWRTFLVSGGSAFYVLIYAIFYFVNKLDIVEFIPSLLYFGYTAL 620

  Fly   629 MVFLFFLLTGTIGFFACFWFIRKIYSVVKVD 659
            ||..|:||||||||:|.:.||||||:.||:|
Zfish   621 MVLSFWLLTGTIGFYAAYVFIRKIYAAVKID 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_001260637.1	EMP70	64..613	CDD:397233	243/571 (43%)
tm9sf4	NP_956804.2	EMP70	59..608	CDD:281048	244/574 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D135708at33208
OrthoFinder	1	1.000	-	-		FOG0000597
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100462
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1983
SonicParanoid	1	1.000	-	-		X358
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.760