Protein Alignment TM9SF2 and TM9SF4

DIOPT Version :9

• Sequence 1: NP_001260637.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_001285907.1
• Gene: TM9SF4 / 34778
• FlyBaseID: FBgn0028541
• Length: 630
• Species: Drosophila melanogaster
• Alignment Length: 679
• Identity: 284/679 - (41%)
• Similarity: 410/679 - (60%)
• Gaps: 75/679 - (11%)

  Fly     5 SGLL--PLLGVVLL-HLATPTQAFYLPGLAPVNFC--KKTDVSSTCKSEILLYVNRLNTEESVIP 64
            ||.|  |.|.:||| .:.....:||:||:|||.|.  :|.||.:.          ::.:..:.:|
  Fly     3 SGALARPCLAIVLLAGVVLVADSFYVPGVAPVEFVQDQKIDVKAV----------KMTSSRTQLP 57

  Fly    65 YEYHHFDFCLGEEQNSPV----ENLGQVVFGERIRPGPYKIQFLENQQCATTCVK-----TYKGD 120
            |:|:...||.  .:|..:    ||||:|:.|:||...||:::..:...|...|.:     |:..:
  Fly    58 YQYYSLRFCY--PKNGTLIFKSENLGEVLRGDRIVNTPYEVRMNQQVNCRLLCNQKDRPLTWSKE 120

  Fly   121 DPASNRRMMVLKKGISLNYQHHWIVDNMPVTWCY-----PLENGKQYCGIGFPMGCLVRSDGEGC 180
            |.|      ::.:.|...|..|.:|||:||....     |.|...::   |:.:|   :.||:..
  Fly   121 DSA------LVAERIQHEYFVHLLVDNLPVATRIVSVNNPAEVTYEH---GYRLG---QVDGDNI 173

  Fly   181 PINSIYNQPMHYYPFNHVDLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKHTDKE--NPNCL 243
            .||            ||:...::||....:.:        |::..:|...|:.|.:.:  ...|.
  Fly   174 YIN------------NHLKFILSYHMHSKDKY--------RVVGFEVETVSVSHKELKFHGDTCN 218

  Fly   244 ---STEPLAISENSLKAGEQLEIVYTYSVKFVKNDSIKWSSRWDYILESMPHTNIQWFSILNSLV 305
               |..|..::.|.     :.::.:||||:: |...:.|:||||..| .|....|.||||:||||
  Fly   219 FPDSARPQLVNPNG-----ETQLYFTYSVEW-KESKVSWASRWDIYL-GMRDVQIHWFSIINSLV 276

  Fly   306 IVLFLSGMVAMIMLRTLHKDIARYNQMDSGEDAQEEFGWKLVHGDVFRPPRKGMLLSVFLGSGVQ 370
            :|.||||::.|||:|||.:||||||..|:.||..||.|||||||||||||:...|.|..:|||:|
  Fly   277 VVFFLSGILTMIMIRTLRRDIARYNTDDNIEDTLEETGWKLVHGDVFRPPKNTRLFSAIIGSGIQ 341

  Fly   371 VLVMAMITLAFACLGFLSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGGLKWKSNVILTSI 435
            :..||:||:.||.||.|||::||||||..:.::|.:||.|||.:||:||:..|.:||....||:.
  Fly   342 IFFMALITIFFAMLGMLSPSSRGALMTSGIFMYVFMGTIAGYYAARLYKTMKGREWKRAAFLTAT 406

  Fly   436 VCPGVVFSLFFVMNLVLWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFRKRALEHPVRT 500
            :.||:||...|.:|..:|.::|||||||:|:|:||.||||:||||.::|.|.|:||:..:|||||
  Fly   407 LYPGIVFGTGFFLNFFIWDKSSSGAVPFTTMISLLLLWFGISVPLVYLGFYLGYRKQPYQHPVRT 471

  Fly   501 NQIPRQIPDQSIYTQPIPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYYMFGFLFLVFVILVITC 565
            |.||||:|.|..|...:...:|.|:||||.:||:|||:.:::|.:|.||:||||||||.|||::|
  Fly   472 NMIPRQVPTQHWYMNAVLSTLMAGILPFGAVFIELFFVFTAIWQNQFYYLFGFLFLVFCILVVSC 536

  Fly   566 SETTILLCYFHLCAEDYHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIKDSASTFLYFGYTAIMV 630
            ::.:|::.||.||.|||.||||||:.||.:|||:..|...||.|||.|.:...|.||.|||.:||
  Fly   537 AQISIVMTYFQLCGEDYRWWWRSFVVSGGSAVYVLFYSIFYFFTKLEITEFIPTLLYLGYTGLMV 601

  Fly   631 FLFFLLTGTIGFFACFWFIRKIYSVVKVD 659
            ..|:||||:|||||.:.||.:||..||:|
  Fly   602 LTFWLLTGSIGFFAAYVFILRIYGAVKID 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_001260637.1	EMP70	64..613	CDD:397233	239/567 (42%)
TM9SF4	NP_001285907.1	EMP70	57..587	CDD:281048	240/570 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461657
Domainoid	1	1.000	404	1.000	Domainoid score	I99
eggNOG	1	0.900	-	-		E1_KOG1278
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	444	1.000	Inparanoid score	I306
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D135708at33208
OrthoFinder	1	1.000	-	-		FOG0000597
OrthoInspector	1	1.000	-	-		mtm9200
orthoMCL	1	0.900	-	-		OOG6_100462
Panther	1	1.100	-	-	P	PTHR10766
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1983
SonicParanoid	1	1.000	-	-		X358
	12	11.830