Protein Alignment TM9SF2 and Tm9sf2

DIOPT Version :10

• Sequence 1: NP_610053.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_001005554.1
• Gene: Tm9sf2 / 306197
• RGDID: 1359230
• Length: 663
• Species: Rattus norvegicus
• Alignment Length: 663
• Identity: 440/663 - (66%)
• Similarity: 529/663 - (79%)
• Gaps: 19/663 - (2%)

  Fly     1 MILLSGLLPLLGVVLLHLATPTQAFYLPGLAPVNFCKKTDVSSTCKSEILLYVNRLNTEESVIPY 65
            ::|||  |.|||.|  ....|..|||||||||||||.:...|:.||:||.|:||||::.|||:||
  Rat    16 LLLLS--LLLLGTV--PGPRPGSAFYLPGLAPVNFCTEEKKSNECKAEIELFVNRLDSVESVLPY 76

  Fly    66 EYHHFDFCLGEEQNSPVENLGQVVFGERIRPGPYKIQFLENQQCATTCVKTYKGDDPASNRRMMV 130
            ||..||||...|...|.||||||:|||||.|.|||..|.:.:.|...|.|||..:.....:::..
  Rat    77 EYTAFDFCQASEGKRPSENLGQVLFGERIEPSPYKFTFNKEETCKLVCTKTYHTEKAEDKQKLDF 141

  Fly   131 LKKGISLNYQHHWIVDNMPVTWCYPLENGKQYCGIGFPMGCLVRSDG---EGCPINSIYNQPMHY 192
            |||.:.||||||||||||||||||.:|:.:::|..|||:||.:...|   :.|.|:|.:::...:
  Rat   142 LKKSMLLNYQHHWIVDNMPVTWCYEVEDNQKFCNPGFPIGCYITDKGHAKDACVISSEFHERDTF 206

  Fly   193 YPFNHVDLEITYHSGQSEDWGIQFGNSG-RIISVKVTPKSIKHTDKENPNCLSTEPLAISENSLK 256
            |.|||||::|.||.       ::.|:.| |:::.|:.|||.:||..:.|:| |...:.||.   |
  Rat   207 YIFNHVDIKIQYHV-------VETGSMGARLVAAKLEPKSFRHTHIDKPDC-SGPAMDISN---K 260

  Fly   257 AGEQLEIVYTYSVKFVKNDSIKWSSRWDYILESMPHTNIQWFSILNSLVIVLFLSGMVAMIMLRT 321
            |..:::|.||||:.|.:..:|:|:|||||||||||||:||||||:||||||||||||||||||||
  Rat   261 ASGEIKIAYTYSISFEEEKNIRWASRWDYILESMPHTHIQWFSIMNSLVIVLFLSGMVAMIMLRT 325

  Fly   322 LHKDIARYNQMDSGEDAQEEFGWKLVHGDVFRPPRKGMLLSVFLGSGVQVLVMAMITLAFACLGF 386
            |||||||||||||.|||||||||||||||:|||||||||||||||||.|:|:|..:||.||||||
  Rat   326 LHKDIARYNQMDSTEDAQEEFGWKLVHGDIFRPPRKGMLLSVFLGSGTQILIMTFVTLFFACLGF 390

  Fly   387 LSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGGLKWKSNVILTSIVCPGVVFSLFFVMNLV 451
            ||||||||||||::||:|.||||||||:||.||||||.|||:||:|||.:|||:||:.||:|||:
  Rat   391 LSPANRGALMTCAVVLWVLLGTPAGYVAARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLI 455

  Fly   452 LWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFRKRALEHPVRTNQIPRQIPDQSIYTQP 516
            ||||.||.|:||.||:|:|||||.:||||||:||||||:|.|:||||||||||||||:||.||:|
  Rat   456 LWGEGSSAAIPFGTLVAILALWFCISVPLTFIGAYFGFKKNAIEHPVRTNQIPRQIPEQSFYTKP 520

  Fly   517 IPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYYMFGFLFLVFVILVITCSETTILLCYFHLCAED 581
            :|||:|||:||||||||||||||:|:||.|:|||||||||||:||||||||.|||||||||||||
  Rat   521 LPGIIMGGILPFGCIFIQLFFILNSIWSHQMYYMFGFLFLVFIILVITCSEATILLCYFHLCAED 585

  Fly   582 YHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIKDSASTFLYFGYTAIMVFLFFLLTGTIGFFACF 646
            |||.|||||||||||||..:|..|||.:||.|..:|||.||||||.|||.:|||.||||||||||
  Rat   586 YHWQWRSFLTSGFTAVYFLVYAIHYFFSKLQITGTASTILYFGYTMIMVLIFFLFTGTIGFFACF 650

  Fly   647 WFIRKIYSVVKVD 659
            ||:.|||||||||
  Rat   651 WFVTKIYSVVKVD 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_610053.1	EMP70	64..613	CDD:460774	368/552 (67%)
Tm9sf2	NP_001005554.1	EMP70	75..619	CDD:460774	369/554 (67%)