Protein Alignment TM9SF2 and Tm9sf5

DIOPT Version :9

• Sequence 1: NP_001260637.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: XP_006528071.1
• Gene: Tm9sf5 / 245423
• MGIID: 2685210
• Length: 678
• Species: Mus musculus
• Alignment Length: 650
• Identity: 295/650 - (45%)
• Similarity: 433/650 - (66%)
• Gaps: 13/650 - (2%)

  Fly    13 VVLLHLATPTQAFYLPGLAPVNFCKKTDVSSTCKSEILLYVNRLNTEESVIPYEYHHFDFCLGEE 77
            ::|..|||...||:.|||.||.:|::...:|.|||.|.:|.::|.:.:||:.|:|..||||....
Mouse    39 LLLCFLATTCDAFFFPGLVPVTYCEEGHPNSYCKSSIQVYADKLYSVDSVMFYDYDSFDFCQDSL 103

  Fly    78 QNSPVENLGQVVFGERIRPGPYKIQFLENQQCATTCVKTYKGDDPASNRRMMVLKKGISLNYQHH 142
            :.:|.|.|||::|||::...|||..|.:::.|...|||:|..|:.....::..|||||..:|:||
Mouse   104 KRTPSETLGQILFGEQVTSCPYKFSFNKDETCRKVCVKSYAPDNEDDMNKLAFLKKGIKQDYRHH 168

  Fly   143 WIVDNMPVTWCYPLENGKQYCGIGFPMGCLVRSDGE---GCPINSIYNQPMHYYPFNHVDLEITY 204
            |||||..:.|||..||.:.:|..|||:||......:   .|.||..:|:....|.|||:|:.|||
Mouse   169 WIVDNTGIIWCYDTENEEHHCMSGFPIGCFNAPSDQVKGSCLINPEFNKNNSLYLFNHLDITITY 233

  Fly   205 HSGQSEDWGIQFGNSGRIISVKVTPKSIKHTDKENPNCLSTEPLAISENSLKAGEQLEIVYTYSV 269
            |.  ..|..::.   .::||.:|.|||.||.|:::..| :..|:.|.|...   |.|.::|||||
Mouse   234 HI--ESDTTVKV---AKLISSRVDPKSYKHLDEDHLTC-NEPPMEIPEEDT---ENLNVIYTYSV 289

  Fly   270 KFVKNDSIKWSSRWDYILESMPHTNIQWFSILNSLVIVLFLSGMVAMIMLRTLHKDIARYNQMDS 334
            ||.::.:.:|||..||.|:|...|::||..::||..:||||.|:|.:::||::.:|||::|::..
Mouse   290 KFEESKATEWSSEGDYDLDSTAETSLQWIRLVNSFFVVLFLCGLVVILLLRSIWRDIAKFNRIKI 354

  Fly   335 GEDAQEEFGWKLVHGDVFRPPRKGMLLSVFLGSGVQVLVMAMITLAFACLGFLSPANRGALMTCS 399
            ....:..|||:|:||::||.|..|||||:.||.|.||.:|..::|..|.||||:||::..|:...
Mouse   355 SVYDRRLFGWRLIHGNLFRLPEHGMLLSILLGQGTQVFIMTFLSLFLAGLGFLTPADQNVLVNYG 419

  Fly   400 MVLFVSLGTPAGYVSARIYKSFGGLKWKSNVILTSIVCPGVVFSLFFVMNLVLWGENSSGAVPFS 464
            :||:::|..||||:||::||:|.|:.||.:.:||:::.||:||:..|:|||:||.:.|..|:.|.
Mouse   420 VVLWLALEIPAGYMSAKMYKTFKGINWKMHFLLTTVLFPGIVFADIFIMNLILWMDGSPAAISFC 484

  Fly   465 TLIALLALWFGVSVPLTFVGAYFGFRKRALEHPVRTNQIPRQIPDQSIYTQPIPGIVMGGVLPFG 529
            ||.:|.||:||||.||||:|.|||.|:: .|.||...:.....|.::.:.:....|::|.:||||
Mouse   485 TLASLFALYFGVSTPLTFLGVYFGKREK-FEFPVYAPKHEHGSPQRTFFPKSTITIILGSLLPFG 548

  Fly   530 CIFIQLFFILSSLWSSQIYYMFGFLFLVFVILVITCSETTILLCYFHLCAEDYHWWWRSFLTSGF 594
            |||:||.:||:.:||..:||:|.||.|:|:|.:|:|||.|:|||||.|||||..||||:||||.|
Mouse   549 CIFLQLSYILNRIWSPHMYYLFAFLLLLFLIFMISCSEVTVLLCYFRLCAEDRGWWWRAFLTSSF 613

  Fly   595 TAVYLFIYCCHYFVTKLSIKDSASTFLYFGYTAIMVFLFFLLTGTIGFFACFWFIRKIYSVVKVD 659
            |:.|:|||..|||.|||.:....|||:||||..|:|..|||.|||||||:||:|:..||.|:|.|
Mouse   614 TSAYIFIYVIHYFFTKLQVTSIGSTFMYFGYAFILVLAFFLFTGTIGFFSCFFFVTTIYGVIKED 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_001260637.1	EMP70	64..613	CDD:397233	247/551 (45%)
Tm9sf5	XP_006528071.1	EMP70	91..634	CDD:367285	247/552 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D135708at33208
OrthoFinder	1	1.000	-	-		FOG0000597
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100462
Panther	1	1.100	-	-	O	PTHR10766
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X358
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.790