Protein Alignment TM9SF2 and tag-123

DIOPT Version :9

• Sequence 1: NP_001260637.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_509429.1
• Gene: tag-123 / 181096
• WormBaseID: WBGene00006472
• Length: 655
• Species: Caenorhabditis elegans
• Alignment Length: 658
• Identity: 394/658 - (59%)
• Similarity: 500/658 - (75%)
• Gaps: 18/658 - (2%)

  Fly    10 LLGVVLLHLATPTQAFYLPGLAPVNFCKKTDVSSTCKSEILLYVNRLNTEESVIPYEYHHFDFCL 74
            |..::|:.......|||||||||||||:..  .:.|.|.|.||||.|:::.||||||||.||||.
 Worm     8 LTKLLLVSFLASASAFYLPGLAPVNFCEVE--KANCPSNISLYVNHLDSDRSVIPYEYHSFDFCT 70

  Fly    75 GEEQNSPVENLGQVVFGERIRPGPYKIQFLENQQCATTC-VKTY---KGDDPASNRRMMVLKKGI 135
            ..|..|||||||||:|||||||.|||:.||:.::|...| .|.|   ..||.|   ::.:|::.:
 Worm    71 VNEDESPVENLGQVLFGERIRPSPYKVAFLQEEKCRLVCDTKKYARGSADDLA---KLRLLQRAM 132

  Fly   136 SLNYQHHWIVDNMPVTWCYPLENGKQYCGIGFPMGCLVRSDG---EGCPINSIYNQPMHYYPFNH 197
            :|||||||||||||||:|:........|..|||:||.|...|   :.|.:|..|..|.::|.|||
 Worm   133 TLNYQHHWIVDNMPVTFCFKNLQNMDVCTTGFPVGCFVDEQGYQHDACVLNQKYKTPNNFYIFNH 197

  Fly   198 VDLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKHTDKENPNCL-STEPLAISENSLKAGEQL 261
            ||:||.|....::...::....||||.:.|.|:||||:...:.:|. |.||:||...|    |..
 Worm   198 VDIEIYYRDMTNDGNFLEHKVGGRIIRIDVKPRSIKHSSSSSLDCSDSAEPIAIDAKS----ESA 258

  Fly   262 EIVYTYSVKFVKNDSIKWSSRWDYILESMPHTNIQWFSILNSLVIVLFLSGMVAMIMLRTLHKDI 326
            ||.|:||:|:.|.| |||||||||||:||||||||||||:|||||||||:|||.||::||||:||
 Worm   259 EITYSYSIKWTKTD-IKWSSRWDYILQSMPHTNIQWFSIMNSLVIVLFLTGMVGMIIMRTLHRDI 322

  Fly   327 ARYNQMDSGEDAQEEFGWKLVHGDVFRPPRKGMLLSVFLGSGVQVLVMAMITLAFACLGFLSPAN 391
            .|||::|:.||||||||||||||||||.||..||||||:|:|.|.|:|..:||.|||||||||||
 Worm   323 DRYNRLDTEEDAQEEFGWKLVHGDVFRTPRYPMLLSVFIGAGCQTLLMVSVTLVFACLGFLSPAN 387

  Fly   392 RGALMTCSMVLFVSLGTPAGYVSARIYKSFGGLKWKSNVILTSIVCPGVVFSLFFVMNLVLWGEN 456
            ||:|:|.::..:|..|..|||:|||:||:|.|:.||:|:::|:.:.||::|::||..|.:||.:.
 Worm   388 RGSLITFALFFYVLFGIVAGYISARLYKTFEGIHWKTNLVMTAFLVPGILFTIFFFSNTLLWTKG 452

  Fly   457 SSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFRKRALEHPVRTNQIPRQIPDQSIYTQPIPGIV 521
            ||.||||.||:.||.||..:|||:|||||||||:||.:|.|||||:||||:|:|:.||:|:||::
 Worm   453 SSAAVPFGTLLVLLVLWIFISVPMTFVGAYFGFKKRGIEAPVRTNKIPRQVPEQTFYTKPLPGML 517

  Fly   522 MGGVLPFGCIFIQLFFILSSLWSSQIYYMFGFLFLVFVILVITCSETTILLCYFHLCAEDYHWWW 586
            |||:||||||||||||||:|:|:.|.||||||||||::||:|||||.||||.|||||||||||||
 Worm   518 MGGILPFGCIFIQLFFILNSIWAHQTYYMFGFLFLVYLILIITCSEATILLAYFHLCAEDYHWWW 582

  Fly   587 RSFLTSGFTAVYLFIYCCHYFVTKLSIKDSASTFLYFGYTAIMVFLFFLLTGTIGFFACFWFIRK 651
            |||:||||||:||||||.|:|.|||:|..:.||.|||.||:|.||:|||:||||||.|.::|:||
 Worm   583 RSFMTSGFTAIYLFIYCIHFFNTKLTISGTISTILYFSYTSIFVFMFFLMTGTIGFLATYYFVRK 647

  Fly   652 IYSVVKVD 659
            ||..||||
 Worm   648 IYGSVKVD 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_001260637.1	EMP70	64..613	CDD:397233	338/556 (61%)
tag-123	NP_509429.1	EMP70	60..611	CDD:281048	339/558 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	722	1.000	Domainoid score	I40
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	833	1.000	Inparanoid score	I235
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D135708at33208
OrthoFinder	1	1.000	-	-		FOG0000597
OrthoInspector	1	1.000	-	-		oto19829
orthoMCL	1	0.900	-	-		OOG6_100462
Panther	1	1.100	-	-	LDO	PTHR10766
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1983
SonicParanoid	1	1.000	-	-		X358
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.870