Protein Alignment TM9SF2 and Y41D4A.4

DIOPT Version :10

• Sequence 1: NP_610053.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_001368302.1
• Gene: Y41D4A.4 / 176983
• WormBaseID: WBGene00021506
• Length: 589
• Species: Caenorhabditis elegans
• Alignment Length: 621
• Identity: 192/621 - (30%)
• Similarity: 299/621 - (48%)
• Gaps: 120/621 - (19%)

  Fly    48 EILLYVNRL----NTEESVIPYEYHHFDFCLGE--EQNSPVENLGQVVFGERIRPGPYKIQFLEN 106
            |::|::|.:    |.:|:   |.|....||.||  |.....|.:|:.:.|..:......|:|..|
 Worm    29 EVVLWMNTVGPYSNRQET---YTYFSLPFCKGEKKEIGHYHETMGESLLGVELEFSGLDIKFRTN 90

  Fly   107 QQCATTCVKTYKGDDPASNRRMMVLKKGISLNYQHHWIVDNMPVTWCYPLENGKQYCGIGFPMGC 171
            .:....|.|.....|      ...|...|..:|.:...:|:||: |                 |.
 Worm    91 TKKTVVCEKKLTETD------YKTLLYAIQNSYYYQMYLDDMPI-W-----------------GM 131

  Fly   172 LVRSDGEGCPINSIYNQPMHYYPFNHVDLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKHTD 236
            :    ||   |::..|.|. |..:.|..|:|.|:..|..|  :.....||:
 Worm   132 V----GE---IDNTVNPPA-YKLYTHKRLDIGYNDKQVVD--VNLTTDGRV-------------- 172

  Fly   237 KENPNCLSTEPLAISENSLKAGEQLEIVYTYSVKFVKNDSIKWSSRWD-YILESMPHTNIQWFSI 300
                             .::.|  .|:.:||.|::.|:: :.::.|:| |:..|.....|.||||
 Worm   173 -----------------DIRPG--AELTFTYEVQWSKSE-VDFTKRFDKYLDPSFFQHRIHWFSI 217

  Fly   301 LNSLVIVLFLSGMVAMIMLRTLHKDIARYNQMDSGEDAQ----EEFGWKLVHGDVFRPPRKGMLL 361
            .||.::|:||.|:|.||::|||.||.|||.:.||.:|..    :|:|||.|||||||||...:|.
 Worm   218 FNSFMMVVFLVGLVWMILVRTLRKDYARYQKEDSLDDLDADLGDEYGWKQVHGDVFRPPSMPLLF 282

  Fly   362 SVFLGSGVQVLVMAMITLAFACLG-FLSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGGLK 425
            |..:|:|..|..:|:||...|.:| |.:  .||:|::.::.::.:.....||....:|..|||..
 Worm   283 SSCIGAGYHVFTVAVITTILAIVGEFYT--ERGSLLSAAIFVYAACSPVNGYAGGSMYARFGGRH 345

  Fly   426 WKSNVILTSIVCPGVVFSLFFVMNLVLWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFR 490
            |...::|.:.:.|.:|..:.|::|.:....::|.|:||:.::|:.|:...|.:|||.||...| |
 Worm   346 WIKQMLLGAFLLPSMVCGVAFLINFIAIYYHASRAIPFTIMLAVSAICLFVILPLTLVGTVIG-R 409

  Fly   491 KRA--LEHPVRTNQIPRQIPDQSIYTQPIPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYYMFGF 553
            ..|  .::|.|.|.:||.|||:..:.||....:.|||||||.|||:::||.:|.|:.:|||::||
 Worm   410 NMAGSADYPCRVNAVPRPIPDKKWFVQPWLITLAGGVLPFGSIFIEMYFIFTSFWAYKIYYVYGF 474

  Fly   554 LFLVFVILVITCSETTILLCYFHLCAEDYHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIKDSAS 618
            :.||.:||.|.....||:..||.|.||||.|.|.||.....||.|:::|..:||..|..
 Worm   475 MLLVTIILSIVTVCVTIVCSYFLLNAEDYRWRWTSFACGASTAFYVYMYSMYYFFFKTK------ 533

  Fly   619 TFLYFGYTAIMVFLFFLLTGTIGFFACFW--FIRKI 652
                                    :|||:  .:|||
 Worm   534 ------------------------YACFYSKLLRKI 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_610053.1	EMP70	64..613	CDD:460774	181/558 (32%)
Y41D4A.4	NP_001368302.1	EMP70	46..533	CDD:460774	181/560 (32%)