Protein Alignment TM9SF2 and TM9SF4

DIOPT Version :10

• Sequence 1: NP_610053.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: XP_319176.3
• Gene: TM9SF4 / 1279456
• VectorBaseID: AGAMI1_009031
• Length: 638
• Species: Anopheles gambiae
• Alignment Length: 674
• Identity: 297/674 - (44%)
• Similarity: 405/674 - (60%)
• Gaps: 76/674 - (11%)

  Fly    10 LLGVVLLHLAT-PTQAFYLPGLAPVNFCK--KTDVSSTCKSEILLYVNRLNTEESVIPYEYHHFD 71
            |||:|.|.|.. ...|||:||:|||.|.|  |.||.:.          ::.:..:.:||||:...
Mosquito    17 LLGLVTLVLVVGHCSAFYVPGVAPVEFKKGQKIDVKAV----------KMTSTHTQLPYEYYSLQ 71

  Fly    72 FCLGEEQNSPV----ENLGQVVFGERIRPGPYKIQFLENQQCATTCVKTYKGDDPAS--NRRMMV 130
            .||  .:|...    ||||:|:.|:||...||:::..||.||...|   ...|.|.:  :.:...
Mosquito    72 LCL--PKNGTFVYKSENLGEVLRGDRIVNTPYEVRMAENVQCKLLC---NAKDRPMNWDHEQSAK 131

  Fly   131 LKKGISLNYQHHWIVDNMPV--------TWCYPLENGKQYCGIGFPMGCLVRSDGEGCPINSIYN 187
            :.:.|...|..|.|:||:||        |.....|:|.:          |.:::|....||
Mosquito   132 VAERIRHEYFVHLIIDNLPVATKFVNPDTMELQFEHGYR----------LGQTNGPNVFIN---- 182

  Fly   188 QPMHYYPFNHVDLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKHTDK--ENPNCL---STEP 247
                    ||:...:.||        :...|..|::..:|...||.....  :...|:   :.:|
Mosquito   183 --------NHLRFRLFYH--------LHSENQYRVVGFEVETLSISKNSLSFDGDTCIFPDNPKP 231

  Fly   248 LAISENSLKAGEQLEIVYTYSVKFVKNDSIKWSSRWDYILESMPHTNIQWFSILNSLVIVLFLSG 312
            .|::.|.     :.|:.:||||.: :..|:||:||||..| .|....|.||||:||||:|.||||
Mosquito   232 QAVTPNG-----RTELYFTYSVVW-QESSVKWASRWDIYL-GMNDVQIHWFSIINSLVVVFFLSG 289

  Fly   313 MVAMIMLRTLHKDIARYNQMD--SGEDAQEEFGWKLVHGDVFRPPRKGMLLSVFLGSGVQVLVMA 375
            ::.|||:|||.:|||:||..|  |.||..||.||||||||||||||...|.:..:|||:|:..||
Mosquito   290 ILTMIMVRTLRRDIAKYNTDDSISIEDTLEETGWKLVHGDVFRPPRYPRLFAAVIGSGIQIFFMA 354

  Fly   376 MITLAFACLGFLSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGGLKWKSNVILTSIVCPGV 440
            :||:..|.||.|||::||||||..::|:|.:|..|||.|||:||:..|..|:....||:...||:
Mosquito   355 LITIFIAMLGMLSPSSRGALMTAGIMLYVFMGLIAGYFSARLYKTMKGRNWERAAFLTATFYPGL 419

  Fly   441 VFSLFFVMNLVLWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFRKRALEHPVRTNQIPR 505
            ||...|.:|..:|.::|||||||.|::|||.||||:|:||.::|.|||:||:|.:||||||.|||
Mosquito   420 VFGTCFFLNFFIWDKDSSGAVPFGTMVALLLLWFGISLPLVYLGYYFGYRKQAYQHPVRTNMIPR 484

  Fly   506 QIPDQSIYTQPIPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYYMFGFLFLVFVILVITCSETTI 570
            |||.|..|......|:|.|:||||.:||:||||.|::|.:|.||:||||||||.|||::||:.:|
Mosquito   485 QIPHQHWYMNVGLCILMAGILPFGAVFIELFFIFSAIWQNQFYYLFGFLFLVFCILVVSCSQISI 549

  Fly   571 LLCYFHLCAEDYHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIKDSASTFLYFGYTAIMVFLFFL 635
            ::.||.||||||.||||||:.||.:|||:..|...||.|||.|.:...|.||.|||.:||..|::
Mosquito   550 VMTYFQLCAEDYRWWWRSFIVSGGSAVYILFYSIFYFFTKLEITEFIPTLLYLGYTGLMVVTFYI 614

  Fly   636 LTGTIGFFACFWFIRKIYSVVKVD 659
            |||||||||.:.||||||..||:|
Mosquito   615 LTGTIGFFAAYSFIRKIYGAVKID 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_610053.1	EMP70	64..613	CDD:460774	250/569 (44%)
TM9SF4	XP_319176.3	None