Protein Alignment TM9SF2 and Tm9sf3

DIOPT Version :10

• Sequence 1: NP_610053.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_579930.1
• Gene: Tm9sf3 / 107358
• MGIID: 1914262
• Length: 587
• Species: Mus musculus
• Alignment Length: 629
• Identity: 195/629 - (31%)
• Similarity: 316/629 - (50%)
• Gaps: 92/629 - (14%)

  Fly    46 KSEILLYVNRL----NTEESVIPYEYHHFDFCLGEEQNSP--VENLGQVVFGERIRPGPYKIQFL 104
            |.|::|::|.:    |.:|:   |:|....||:|.:::..  .|.||:.:.|..:......|:|.
Mouse    36 KEEVVLWMNTVGPYHNRQET---YKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFK 97

  Fly   105 ENQQCATTCVKTYKGDDPASNRRMMVLKKGISLNYQHHWIVDNMPVTWCYPLENGKQYCGIGFPM 169
            ::....|.|    :.|.....|...|.  .|..:|.:...:|::|: |
Mouse    98 DDVMPGTYC----EIDLDKEKRDAFVY--AIKNHYWYQMYIDDLPI-W----------------- 138

  Fly   170 GCLVRSDGEGCPINSIYNQPMHYYPFNHVDLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKH 234
            |.:..:|..|          ..||.:.:..|||.:             |..||:.|.:|
Mouse   139 GIVGEADENG----------EDYYLWTYKKLEIGF-------------NGNRIVDVNLT------ 174

  Fly   235 TDKENPNCLSTEPLAISENSLKAGEQLEIVYTYSVKFVKNDSIKWSSRWD-YILESMPHTNIQWF 298
                            ||..:|.....:|..:||||:.|:| :|:..|:| |:..|.....|.||
Mouse   175 ----------------SEGKVKLVPNTKIQMSYSVKWKKSD-VKFEDRFDKYLDPSFFQHRIHWF 222

  Fly   299 SILNSLVIVLFLSGMVAMIMLRTLHKDIARYNQM----DSGEDAQEEFGWKLVHGDVFRPPRKGM 359
            ||.||.::|:||.|:|:||::|||.||.|||::.    |...|..:|:|||.||||||||....:
Mouse   223 SIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPL 287

  Fly   360 LLSVFLGSGVQVLVMAMITLAFACLGFLSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGGL 424
            :.|..:|||.|:..:::|.:..|.:..|. ..||::::.::.::.:.....||....:|...||.
Mouse   288 IFSSLIGSGCQIFAVSLIVIIVAMIEDLY-TERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGR 351

  Fly   425 KWKSNVILTSIVCPGVVFSLFFVMNLVLWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGF 489
            :|...:.:.:.:.|.:|....|.:|.:....::|.|:||.|::|:..:.|.|.:||..||...|
Mouse   352 RWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILG- 415

  Fly   490 RKRAL----EHPVRTNQIPRQIPDQSIYTQPIPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYYM 550
              |.|    ..|.|.|.:||.||::..:.:|...:.:||:||||.|||:::||.:|.|:.:|||:
Mouse   416 --RNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYV 478

  Fly   551 FGFLFLVFVILVITCSETTILLCYFHLCAEDYHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIKD 615
            :||:.||.|||.|.....||:..||.|.||||.|.|.|||::..||:|:::|..:|:..|..:..
Mouse   479 YGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYG 543

  Fly   616 SASTFLYFGYTAIMVFLFFLLTGTIGFFACFWFIRKIYSVVKVD 659
            ...|..||||.|:......::.|.||:.....|:||||:.||:|
Mouse   544 LFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_610053.1	EMP70	64..613	CDD:460774	172/559 (31%)
Tm9sf3	NP_579930.1	EMP70	55..525	CDD:460774	167/546 (31%)