Protein Alignment TM9SF2 and tm9sf3

DIOPT Version :10

• Sequence 1: NP_610053.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: XP_002936010.2
• Gene: tm9sf3 / 100491663
• XenbaseID: XB-GENE-6033854
• Length: 579
• Species: Xenopus tropicalis
• Alignment Length: 630
• Identity: 193/630 - (30%)
• Similarity: 316/630 - (50%)
• Gaps: 94/630 - (14%)

  Fly    46 KSEILLYVNRL----NTEESVIPYEYHHFDFCLGEEQNSP--VENLGQVVFGERIRPGPYKIQFL 104
            |.|::|::|.:    |.:|:   |:|....||:|.:::..  .|.||:.:.|..:......|:|.
 Frog    28 KEEVVLWMNTVGPYHNRQET---YKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFK 89

  Fly   105 ENQQCATTC-VKTYKGDDPASNRRMMVLKKGISLNYQHHWIVDNMPVTWCYPLENGKQYCGIGFP 168
            ::....:.| :...||...|       ....|..:|.:...:|::|: |
 Frog    90 DDVMQTSYCEIDLTKGKKDA-------FVYAIKNHYWYQMYIDDLPI-W---------------- 130

  Fly   169 MGCLVRSDGEGCPINSIYNQPMHYYPFNHVDLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIK 233
             |.:..:|..|          ..||.:.:..|||.|             |..||:.|.:|
 Frog   131 -GIVGEADENG----------EDYYLWTYKKLEIGY-------------NGNRIVDVNLT----- 166

  Fly   234 HTDKENPNCLSTEPLAISENSLKAGEQLEIVYTYSVKFVKNDSIKWSSRWD-YILESMPHTNIQW 297
                             ||..:|.....::..:||||:.|:| :::..|:| |:..|.....|.|
 Frog   167 -----------------SEGKVKLVPNTKVQMSYSVKWKKSD-VRFEDRFDKYLDPSFFQHRIHW 213

  Fly   298 FSILNSLVIVLFLSGMVAMIMLRTLHKDIARYNQM----DSGEDAQEEFGWKLVHGDVFRPPRKG 358
            |||.||.::|:||.|:|:||::|||.||.|||::.    |...|..:|:|||.||||||||....
 Frog   214 FSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHP 278

  Fly   359 MLLSVFLGSGVQVLVMAMITLAFACLGFLSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGG 423
            ::.|..:|||.|:..:::|.:..|.:..|. ..||::::.::.::.:.....||....:|...||
 Frog   279 LMFSSLIGSGCQIFAVSLIVIIVAMIEDLY-TERGSMLSTAIFVYAATSPVNGYFGGSLYARQGG 342

  Fly   424 LKWKSNVILTSIVCPGVVFSLFFVMNLVLWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFG 488
            .:|...:.:.:.:.|.:|....|.:|.:....::|.|:||.|::|:..:.|.|.:||..||...|
 Frog   343 RRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILG 407

  Fly   489 FRKRAL----EHPVRTNQIPRQIPDQSIYTQPIPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYY 549
               |.|    ..|.|.|.:||.||::..:.:|...:.:||:||||.|||:::||.:|.|:.:|||
 Frog   408 ---RNLAGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYY 469

  Fly   550 MFGFLFLVFVILVITCSETTILLCYFHLCAEDYHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIK 614
            ::||:.||.|||.|.....||:..||.|.||||.|.|.|||::..||:|:::|..:|:..|..:.
 Frog   470 VYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMY 534

  Fly   615 DSASTFLYFGYTAIMVFLFFLLTGTIGFFACFWFIRKIYSVVKVD 659
            ....|..||||.|:......::.|.||:.....|:||||:.||:|
 Frog   535 GLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_610053.1	EMP70	64..613	CDD:460774	170/560 (30%)
tm9sf3	XP_002936010.2	EMP70	47..517	CDD:460774	165/547 (30%)