Protein Alignment TM9SF2 and tm9sf1

DIOPT Version :10

• Sequence 1: NP_610053.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: XP_002939067.1
• Gene: tm9sf1 / 100486536
• XenbaseID: XB-GENE-992446
• Length: 589
• Species: Xenopus tropicalis
• Alignment Length: 667
• Identity: 195/667 - (29%)
• Similarity: 325/667 - (48%)
• Gaps: 96/667 - (14%)

  Fly     8 LPLLGVVLLHLATPTQAF----YLPGLAPVNFCKKTDVSSTCKSEILLYVNRL----NTEESVIP 64
            |.||.::.:.|..|:.|.    |.||                 ..:::|||::    |.:|:
 Frog     4 LHLLSLLCVWLVAPSPATGDNRYKPG-----------------DPVMMYVNKVGPYHNPQET--- 48

  Fly    65 YEYHHFDFCLGEEQNSPVENLGQVVFGERIRPGPYKIQFLENQQCATTCVKTYKGDDPASNRRMM 129
            |.|:....|..|:.......||:|:.|:|:....|:|.|.:|.:..|.|      :...|..::.
 Frog    49 YHYYQLPVCAPEQIRHKSLTLGEVLDGDRMAESMYRITFRQNVERQTLC------EMKLSLSQVE 107

  Fly   130 VLKKGISLNYQHHWIVDNMPVTWCYPLENGKQYCGIGFPMGCLVRSDGEGCPINSIYNQPMHYYP 194
            .|::.|...|...:::|::|:         :.:.|.....|.|..:...|.
 Frog   108 ELRRAIEELYYFEFVLDDIPI---------RGFLGYMEESGFLPHTHKIGL-------------- 149

  Fly   195 FNHVDLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKHTDKENPNCLSTEPLAISENSLKAGE 259
            :.|:|:.|.|             |..|||...|:.:.:|             |.::.:    ..|
 Frog   150 WAHLDINIEY-------------NDDRIIYSNVSVRDVK-------------PFSLDD----VRE 184

  Fly   260 QLEIVYTYSVKFVKNDSIKWSSRWDYILES--MPHT-NIQWFSILNSLVIVLFLSGMVAMIMLRT 321
            .|.:.:|||:.:..: ::.:..|.|.:.:|  .|.: .|.|.||:||:|:|..|.|.|.:|::|.
 Frog   185 TLSLTHTYSIHWFPS-TVTYERRGDRLRDSSFFPKSLEIHWLSIINSMVLVFLLLGFVVIILMRV 248

  Fly   322 LHKDIARYNQMDSGEDAQE--EFGWKLVHGDVFR-PPRKGMLLSVFLGSGVQVLVMAMITLAFAC 383
            |..|:||||..:.|.|..|  :.|||::|.|||| ||.:.:|.:| ||.|.|.|.:....:....
 Frog   249 LKSDLARYNLDEEGADDMEQGDNGWKIIHTDVFRFPPYRSLLCAV-LGVGFQFLALGTGIIVMVL 312

  Fly   384 LGFLSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGGLKWKSNVILTSIVCPGVVFSLFFVM 448
            ||..:....||:.:.:::|:......:||||:..|:..||.:|..|::||:.:.....|..:.|:
 Frog   313 LGLFNVHRHGAINSAAILLYALTCCVSGYVSSNFYRQLGGDRWVWNIVLTTSLFSAPFFLTWSVV 377

  Fly   449 NLVLWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFRKRA-LEHPVRTNQIPRQIPDQSI 512
            |.|.|...|:.|:|.:|::.||.:|..|..|||.:|..||..... .|.|.||..|.|:||.|..
 Frog   378 NSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNSAVNFEAPCRTKNIAREIPRQPW 442

  Fly   513 YTQPIPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYYMFGFLFLVFVILVITCSETTILLCYFHL 577
            |......:.:||.|||..|.::|::|.:::|..:.|.::|.||:||.||:...:..::.|.||.|
 Frog   443 YKSAPVHMAIGGFLPFSAISVELYYIFATVWGREQYTLYGILFIVFAILLSVGACISVALTYFQL 507

  Fly   578 CAEDYHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIKDSASTFLYFGYTAIMVFLFFLLTGTIGF 642
            ..|||.|||||.|::|.|..::|:|...|:..:.::.....|..:|||:.:..::|||:.|.:.|
 Frog   508 SGEDYRWWWRSVLSTGSTGAFIFLYSVFYYWRRSNMSGVVQTVEFFGYSFLTAYVFFLMLGAVSF 572

  Fly   643 FACFWFIRKIYSVVKVD 659
            .|...|||.||..:|:|
 Frog   573 TASLRFIRYIYINLKMD 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_610053.1	EMP70	64..613	CDD:460774	164/555 (30%)
tm9sf1	XP_002939067.1	EMP70	48..546	CDD:460774	164/561 (29%)