Protein Alignment TM9SF2 and tm9sf4

DIOPT Version :10

• Sequence 1: NP_610053.1
• Gene: TM9SF2 / 35335
• FlyBaseID: FBgn0032880
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: XP_031750207.1
• Gene: tm9sf4 / 100379964
• XenbaseID: XB-GENE-993565
• Length: 642
• Species: Xenopus tropicalis
• Alignment Length: 672
• Identity: 294/672 - (43%)
• Similarity: 421/672 - (62%)
• Gaps: 54/672 - (8%)

  Fly     6 GLLP-LLGVVLLHLATPTQAFYLPGLAPVNFCKKTDVSSTCKSEILLYVNRLNTEESVIPYEYHH 69
            |||. ||.|.|||   ....||:||:||:||.:...|.        :...:|.:..:.:||||:.
 Frog     7 GLLGLLLSVSLLH---GIGCFYVPGVAPINFLQDAPVD--------IKAVKLTSSRTQLPYEYYS 60

  Fly    70 FDFCLGEEQNSPVENLGQVVFGERIRPGPYKIQFLENQQCATTCVKTYKGDDPASN----RRMMV 130
            ..||...|.....||||:|:.|:||...|:::....:::|...|     |....|:    .:..:
 Frog    61 LPFCQPTEIAYKSENLGEVLRGDRIVNTPFRVLMNSDKKCEVLC-----GGPRQSHVLTVEQSKL 120

  Fly   131 LKKGISLNYQHHWIVDNMPVTWCYPL------ENGKQYCGIGFPMGCLVRSDGEGCPINSIYNQP 189
            :.:.|..:|..|.|.||:||.....|      |..|:...:.|.         .|..:..|.|.
 Frog   121 VAERIREDYYVHLIADNLPVATRLDLYLNREEEEKKKEKDVQFE---------HGYRLGFIDNN- 175

  Fly   190 MHYYPFNHVDLEITYHSGQSEDWGIQFGNSGRIISVKVTPKSIKHTD-KENPNCLSTEPLAISEN 253
             .:|..||:...:.||..:.|:   :...:.|::..:|.|:||:..| |.....|.|.|    ::
 Frog   176 -KFYLHNHLSFYLYYHPEEIEE---KQEPTFRVVRFEVIPQSIRLEDLKGTDQGLCTVP----DS 232

  Fly   254 SLKAGEQLE------IVYTYSVKFVKNDSIKWSSRWDYILESMPHTNIQWFSILNSLVIVLFLSG 312
            |..|.::::      |::||||.:.::| |||:||||..| :|....|.||||:||:|:|.||||
 Frog   233 SSSAPQEIDPSKENKIIFTYSVHWQESD-IKWASRWDTYL-TMSDVQIHWFSIINSVVVVFFLSG 295

  Fly   313 MVAMIMLRTLHKDIARYNQMDSGEDAQEEFGWKLVHGDVFRPPRKGMLLSVFLGSGVQVLVMAMI 377
            :::||::|||.||||.||:.|..||..||.|||||||||||||:..|:||..||||:|:..|.:|
 Frog   296 ILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILI 360

  Fly   378 TLAFACLGFLSPANRGALMTCSMVLFVSLGTPAGYVSARIYKSFGGLKWKSNVILTSIVCPGVVF 442
            .:..|.||.|||::||||||.:..||:.:|...|:.:.|:|::..|.:|:.....|:.:.|||||
 Frog   361 VIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFFAGRLYRTLKGHRWRKGAFCTATLYPGVVF 425

  Fly   443 SLFFVMNLVLWGENSSGAVPFSTLIALLALWFGVSVPLTFVGAYFGFRKRALEHPVRTNQIPRQI 507
            ::.||:|..:||::|||||||.|::|||.:|||:|:||.::|.||||||:..::|||||||||||
 Frog   426 AICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQI 490

  Fly   508 PDQSIYTQPIPGIVMGGVLPFGCIFIQLFFILSSLWSSQIYYMFGFLFLVFVILVITCSETTILL 572
            |:|..|.:...||:|.|:||||.:||:||||.|::|.:|.||:||||||||:|||::||:.:|::
 Frog   491 PEQRWYMKRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVM 555

  Fly   573 CYFHLCAEDYHWWWRSFLTSGFTAVYLFIYCCHYFVTKLSIKDSASTFLYFGYTAIMVFLFFLLT 637
            .||.||||||.||||:||.||.:|.|:.||...|||.||.|.:...:.||||||.:||..|:|||
 Frog   556 VYFQLCAEDYRWWWRTFLVSGGSAFYVLIYAVFYFVNKLDIVEFIPSLLYFGYTTLMVLSFWLLT 620

  Fly   638 GTIGFFACFWFIRKIYSVVKVD 659
            |||||:|.:.||||||:.||:|
 Frog   621 GTIGFYAAYMFIRKIYAAVKID 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF2	NP_610053.1	EMP70	64..613	CDD:460774	247/565 (44%)
tm9sf4	XP_031750207.1	EMP70	55..599	CDD:460774	248/568 (44%)