Protein Alignment CarT and SLC22A13

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_004247.2
• Gene: SLC22A13 / 9390
• HGNCID: 8494
• Length: 551
• Species: Homo sapiens
• Alignment Length: 550
• Identity: 154/550 - (28%)
• Similarity: 253/550 - (46%)
• Gaps: 63/550 - (11%)

  Fly    39 LLPTIGEFGKYQKLLVFGIC-LPACIPCGFCAFNQLFMA-DTPDDYWCRIP----ELLDLPLEQR 97
            :|..||:||::|..|:..:| |....|  |..|..:||. |.|  :.|.:.    ...:|...::
Human     7 VLAEIGDFGRFQIQLLILLCVLNFLSP--FYFFAHVFMVLDEP--HHCAVAWVKNHTFNLSAAEQ 67

  Fly    98 KSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEP---NASWPLI---------KCP 150
            ..||:|  ||.                    :|..:......|   |||...|         .|.
Human    68 LVLSVP--LDT--------------------AGHPEPCLMFRPPPANASLQDILSHRFNETQPCD 110

  Fly   151 QGWEYNTSVVWSSIVIDFDLVCD----QDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFV 211
            .||||..:.: .|:..:|:||||    :|...::.:|.|    .||..:||.|.||.||:.:...
Human   111 MGWEYPENRL-PSLKNEFNLVCDRKHLKDTTQSVFMAGL----LVGTLMFGPLCDRIGRKATILA 170

  Fly   212 CLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTS 276
            .|.......|.|:....|..:...|..|...:..:......:..|.||.::|:...|:....::.
Human   171 QLLLFTLIGLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSL 235

  Fly   277 GIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGR 341
            |.|:|:|:.|..|:|..|....:.|....|.|.:.:|||.||||.|||::||::::::.|.||.|
Human   236 GQMVLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRR 300

  Fly   342 EFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYG 406
                    ||..::....:.::.....|.  .||.|.|.:|..|::|...||.:...|.|||...
Human   301 --------KLSPELMNQLVPEKTGPSGNA--LDLFRHPQLRKVTLIIFCVWFVDSLGYYGLSLQV 355

  Fly   407 PALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLV 471
            ...|.:.|::..:...||:|:.....:.|..:||:|....:::|||:.|:|.:.:|.|......:
Human   356 GDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIFIPADLPVVVTM 420

  Fly   472 LYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIM 536
            |.:|.|...:|:|.|.|.::.||:||.:|..|:|.......:|.|..|.:..||:.:..||::|.
Human   421 LAVVGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIY 485

  Fly   537 GFLSMLGGMTGLRLPETLHHRLPQTIEEGE 566
            |.|.::.|:....||||....|..|:::.|
Human   486 GSLPIVAGLLCTLLPETHGQGLKDTLQDLE 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	117/402 (29%)
		xylE	<306..>342	CDD:182225	17/35 (49%)
SLC22A13	NP_004247.2	MFS_OAT	102..500	CDD:340932	118/412 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..551		0/4 (0%)