DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CarT and HXT2

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_013724.1	Gene:	HXT2 / 855023	SGDID:	S000004613	Length:	541	Species:	Saccharomyces cerevisiae

Alignment Length:	499	Identity:	120/499 - (24%)
Similarity:	188/499 - (37%)	Gaps:	146/499 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 QLLESGEEDDLTTME---------PNASWPLIKC----------PQGWEYNTSVVWSSIV--IDF 168
            |.||:.|....|..|         |.|::..:.|          ..||:..|.   |..|  .||
Yeast    25 QKLETDESPIQTKSEYTNAELPAKPIAAYWTVICLCLMIAFGGFVFGWDTGTI---SGFVNQTDF 86

  Fly   169 -----DLVCDQDIYPTIGLAALNTGGPVGVY---------LFGLLNDRGGRRLSYFVCLATLLAG 219
                 .:..|...|    |:.:.||..||::         ..|.|.|..|||:.....:...:.|
Yeast    87 KRRFGQMKSDGTYY----LSDVRTGLIVGIFNIGCAFGGLTLGRLGDMYGRRIGLMCVVLVYIVG 147

  Fly   220 SLMTSLSKDFW-TWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFY----TSGIM 279
            .::...|.|.| .:...|:|.|:.:..:    .::|..|:.|.....:.....:||    |.||.
Yeast   148 IVIQIASSDKWYQYFIGRIISGMGVGGI----AVLSPTLISETAPKHIRGTCVSFYQLMITLGIF 208

  Fly   280 LLSGVTYLERDW---VRLSYITSLPF-YAYFLY--MFVMPESPRWLLMRGRLEEALKILERMAKV 338
            |.....|..:|:   |:......|.| :|.|:.  |.::|||||:|:.:||.|:|.:.|.:..||
Yeast   209 LGYCTNYGTKDYSNSVQWRVPLGLNFAFAIFMIAGMLMVPESPRFLVEKGRYEDAKRSLAKSNKV 273

  Fly   339 NGREFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSW---FANE---- 396
            . .|.|..|       ...|.:      ||||           ..:.:....||   |:|:
Yeast   274 T-IEDPSIV-------AEMDTI------MANV-----------ETERLAGNASWGELFSNKGAIL 313

  Fly   397 -TVYLGLS--------------YYGP----ALG-TNQYVSFFLSAVVELPSYLCCWYFMDTWGRR 441
             .|.:|:.              |||.    |:| .:.:.:..:..:|...|.....|.:|.:|||
Yeast   314 PRVIMGIMIQSLQQLTGNNYFFYYGTTIFNAVGMKDSFQTSIVLGIVNFASTFVALYTVDKFGRR 378

  Fly   442 WPLSLSMILGGVACV-----------ITVMLPD-------DAVDETLV----LYLVSKALLSASF 484
                 ..:|||.|.:           :|.:.|:       .|....::    |::...|:..|.
Yeast   379 -----KCLLGGSASMAICFVIFSTVGVTSLYPNGKDQPSSKAAGNVMIVFTCLFIFFFAISWAP- 437

  Fly   485 LIIYPFAGELYPTQVR----GIGIGASSYIGGLGLIGI--PFIT 522
             |.|....|.||.:|:    .|.:|| ::|.|. |||.  ||||
Yeast   438 -IAYVIVAESYPLRVKNRAMAIAVGA-NWIWGF-LIGFFTPFIT 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	120/499 (24%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	102/416 (25%)
HXT2	NP_013724.1	Sugar_tr	59..519	CDD:395036	111/465 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000