DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CarT and PHO84

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_013583.1	Gene:	PHO84 / 854916	SGDID:	S000004592	Length:	587	Species:	Saccharomyces cerevisiae

Alignment Length:	574	Identity:	137/574 - (23%)
Similarity:	212/574 - (36%)	Gaps:	159/574 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 PLEQRKSLSIPKELDNDELVYSKCYTYGVNWTQL--LESGEEDDLTTMEPNASWPLIKCPQGWEY 155
            |||:|:   :..|..:||         |..|.|:  :.......||.     |:.:.....|...
Yeast    42 PLERRR---LALESIDDE---------GFGWQQVKTISIAGVGFLTD-----SYDIFAINLGITM 89

  Fly   156 NTSVVWSSIVIDFDLVCDQDIYPTIGLAALNT--GGPVGVYLFGLLNDRGGRRLSY-------FV 211
            .:.|.|...:..          |:..|..::|  |..:|.:.||.|.|..||:..|       .|
Yeast    90 MSYVYWHGSMPG----------PSQTLLKVSTSVGTVIGQFGFGTLADIVGRKRIYGMELIIMIV 144

  Fly   212 CLATLLAGSLMTSLSKDF---WTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTF 273
            |  |:|..::..|.:.:|   .|:  .|:::|:.|...|.:..||:.|.....:|.  .:|...|
Yeast   145 C--TILQTTVAHSPAINFVAVLTF--YRIVMGIGIGGDYPLSSIITSEFATTKWRG--AIMGAVF 203

  Fly   274 -------YTSGIMLL--------------SGV-------TYLERDWVRLSYITSLPFYAYFLYMF 310
                   .:.||:.|              ||.       ...::.|..|..:.::...|...:..
Yeast   204 ANQAWGQISGGIIALILVAAYKGELEYANSGAECDARCQKACDQMWRILIGLGTVLGLACLYFRL 268

  Fly   311 VMPESPRWLL-MRGRLEEALKILER-------------MAKVNGREFPEAVHLKLEAQIRRDKLK 361
            .:|||||:.| :..:||.|....|:             || :||.|         .|....:.|.
Yeast   269 TIPESPRYQLDVNAKLELAAAAQEQDGEKKIHDTSDEDMA-INGLE---------RASTAVESLD 323

  Fly   362 KQKKKMANVGLADLCR-TPNMRLKTILITL--SWFANETVYLGLSY--------YGPALGTNQYV 415
            ....|   ....|.|| ....:...||:..  |||..:..:.|||.        .|.|...|.|.
Yeast   324 NHPPK---ASFKDFCRHFGQWKYGKILLGTAGSWFTLDVAFYGLSLNSAVILQTIGYAGSKNVYK 385

  Fly   416 SFFLSAV--------VELPSYLCCWYFMDTWGRRWPLSLS--MILGGVACVITV---MLPDDAVD 467
            ..:.:||        ..||.|....:.:|..||: |:.|:  :||..:.|||..   .|.|..:
Yeast   386 KLYDTAVGNLILICAGSLPGYWVSVFTVDIIGRK-PIQLAGFIILTALFCVIGFAYHKLGDHGL- 448

  Fly   468 ETLVLYLVSKALL-----SASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLG-- 525
              |.||::.:...     :.:|::    .||.:||:.|....|.|:..|.:|.|...  |.||
Yeast   449 --LALYVICQFFQNFGPNTTTFIV----PGECFPTRYRSTAHGISAASGKVGAIIAQ--TALGTL 505

  Fly   526 ------KD----NLKLPLV--IMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEE 567
                  :|    |..||.|  |.....:||..|.|.:|||..    :|:||..|
Yeast   506 IDHNCARDGKPTNCWLPHVMEIFALFMLLGIFTTLLIPETKR----KTLEEINE 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	133/566 (23%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	113/465 (24%)
PHO84	NP_013583.1	2A0109	49..554	CDD:129965	132/561 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
TreeFam	0	0.000	Not matched by this tool.
	1	1.000