DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CarT and OCT2

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_178054.1	Gene:	OCT2 / 844274	AraportID:	AT1G79360	Length:	527	Species:	Arabidopsis thaliana

Alignment Length:	527	Identity:	133/527 - (25%)
Similarity:	217/527 - (41%)	Gaps:	74/527 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 PLEQRKSLSIPKELDNDELVYSKCYTYGVNWTQLLE------SGEEDD-------LTTMEPNASW 144
            ||....:.|.|:.|  |:.:.|...::|  |.|.|:      ||..|.       .|..||  :|
plant     7 PLLTDSNSSSPRSL--DDTIESYIGSFG--WAQFLQAALVSFSGVFDAQQTFISVFTDSEP--TW 65

  Fly   145 P-----------------LIKCPQGWEYNTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVG 192
            .                 |.|....|:|:..|   |::.::.|.|.......:..::...|..:|
plant    66 HCTDSNSICHESISNICILPKTAWSWDYSPHV---SVISEWGLQCAGSFVKGLPESSFFVGCLIG 127

  Fly   193 VYLFGLLNDRG-GRRLSYFVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLE 256
            ..:...|.|.. ||:...|:....:...:::|..|.:.|.:|..|.:.|.....:.....::|.|
plant   128 GLVLSTLADSSLGRKNMLFLSCLVMAISTMLTVFSPNIWVYAVLRFVNGFGRATIGTCALVLSTE 192

  Fly   257 LVGENYRSFVTVMTCTFYTSGIMLLSGVTYLER--DWVRLSYITSLPFYAY-FLYMFVMPESPRW 318
            |||:.:|..|.:|:...:..|.:.|..:.|:.|  .|..|...||:|...| .|..|.:.|||||
plant   193 LVGKKWRGRVGIMSFFGFMLGFLSLPLMAYMNRGSSWRILYAWTSIPTIIYCVLVRFFVCESPRW 257

  Fly   319 LLMRGRLEEALKILERMAKVNGREFPE--AVHLKLEA-QIRRDKLKKQKKKMANVGLADLCRTPN 380
            |.:|||.|||:.||:|:|.:...:...  |:.:...: ....|    ::|...||.:....:
plant   258 LFVRGRREEAISILKRVASIPSTDVSSGGAISMSFSSLPFEED----EEKPSTNVNIFTTMK--- 315

  Fly   381 MRLKTILITLSWFANE-------TVYLGLSYYGPALGT-----NQYVSFFLSAVVELPSYLCCWY 433
                 :|:...|....       ...:||.|||..|..     |.|:|...:|:::||:.|...:
plant   316 -----VLVEKRWALKRLSAVMAIAFGIGLVYYGMPLALSNLDFNIYLSAAFNALMDLPANLITLF 375

  Fly   434 FMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDE----TLVLYLVSKALLSASFLIIYPFAGEL 494
            .:|...||..|.....||||:.|:...|.:..:..    .|.|.|:|.....::|.:...:..||
plant   376 LVDKLSRRNALIGFTALGGVSSVLIFALHNMRIGNHGALQLALELISYFSACSAFNMEMIYTIEL 440

  Fly   495 YPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLP 559
            :||.||...|..:.....||.:..|.:...|:.|......:.|....|.|:..:.||||....|.
plant   441 FPTCVRNSAIAMARQALVLGGVFSPIMVAAGRKNAFWSFGLFGLAIGLLGLFAVGLPETRGSDLC 505

  Fly   560 QTIEEGE 566
            .|::|.|
plant   506 DTMDEEE 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	130/520 (25%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	99/391 (25%)
OCT2	NP_178054.1	MFS_OCT_plant	79..497	CDD:340936	107/432 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		mtm1022
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.020