DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CarT and OCT3

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_173089.1	Gene:	OCT3 / 838209	AraportID:	AT1G16390	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	483	Identity:	126/483 - (26%)
Similarity:	200/483 - (41%)	Gaps:	71/483 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 DNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWEYNTSVVWSSIVIDFDLV 171
            ||.:.|.|.|.|...|            |.|: ||.:|       .|:.|..|   ||:.::.|.
plant    73 DNSDRVDSVCNTSSSN------------LCTL-PNQTW-------SWDLNPHV---SIISEWGLQ 114

  Fly   172 CDQDIYPTIGLAALNTGGPVGVYLFGLLNDR--GGRRLSYFVCLATLLAGSLMTSLSKDFWTWAG 234
            |..........::...|..:|......|.|.  |.:.:....||...|: |::|:.|...|.:|.
plant   115 CAGSFLKGFPASSFFLGCLIGGLALSTLADSSLGRKNMLLLSCLIMSLS-SMLTAFSTSIWVYAF 178

  Fly   235 SRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSGVTYLE--RDWVRLSYI 297
            .|.:.|.....:.....::|.||||:.:|..|..|....:|.|.:.|..:.|:.  ..|..|...
plant   179 LRFLNGCGRATIGTCALVLSTELVGKKWRGQVGAMGFFCFTLGFLSLPMLGYINEGNSWRNLYVW 243

  Fly   298 TSLP--FYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHL---KLEAQIRR 357
            ||:|  .|...:..||. ||||||:::||.|||:.||:.:|.       .|:.:   .|..::..
plant   244 TSIPTLIYCCLVRSFVR-ESPRWLIVKGRKEEAVSILQSIAS-------NAITMSFTNLCFEVEN 300

  Fly   358 DKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVY-------LGLSYYGPALGT---- 411
            |:.|      :|..:.|..:        ||:..||.....:.       :|:.|||..|..
plant   301 DQSK------SNPDVYDALK--------ILVRKSWSFRRLLAAMVVGFGIGMVYYGMPLALTNLN 351

  Fly   412 -NQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLV 475
             |.|:....:|:.|.|::|..::|:|...||..|.....|.|::..:..:|........:||.||
plant   352 FNLYLGVVFNALSEFPAFLITFFFIDKINRRDALIGFTALSGISSALIAVLGQQLGSLQIVLELV 416

  Fly   476 S--KALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGF 538
            |  .|..:.:..:||..  |::||.||...|.........|.:..|.:...|::|......:.|.
plant   417 SFFSACTAFNMTLIYTI--EMFPTCVRNSAISMVRQALVFGGVFSPVMVAAGRENQFWSYGLFGL 479

  Fly   539 LSMLGGMTGLRLPETLHHRLPQTIEEGE 566
            :..|.|:....||||....|..|::|.|
plant   480 IIGLCGLFVFGLPETRGSVLCDTMDEEE 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	123/476 (26%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	99/391 (25%)
OCT3	NP_173089.1	MFS_OCT_plant	87..492	CDD:340936	112/452 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I1021
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		mtm1022
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.070