Protein Alignment CarT and Slc22a16

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_081848.1
• Gene: Slc22a16 / 70840
• MGIID: 1918090
• Length: 649
• Species: Mus musculus
• Alignment Length: 689
• Identity: 169/689 - (24%)
• Similarity: 304/689 - (44%)
• Gaps: 110/689 - (15%)

  Fly    32 EAFDLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQ 96
            |:.:::.:...||.||::| ::::.||....:.||....:.:|::..| ::.|:.|.::
Mouse     2 ESCNVELIFDHIGHFGRFQ-IVLYLICAYQSLSCGIHYLSSVFLSIIP-EHACKPPGMV------ 58

  Fly    97 RKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDD--LTTMEPNASWPLIKCPQGWEYNTSV 159
            ||:            |:.....:.:.....|.|.|..|  :..::....|.|.:|.:.|..|||.
Mouse    59 RKA------------VFHNVSAWRLEDILALRSPEHKDHIMVELQDGEIWELTRCSRTWRENTSH 111

  Fly   160 V-----------------------W-SSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLN 200
            :                       | :|.|.:|:|||||..|..:....:..|..:|...|..|:
Mouse   112 LGYEYSGYKHDSPCFDGYVYDQSKWRNSAVRNFNLVCDQKWYARMIQPLIIFGVMLGSITFSYLS 176

  Fly   201 DRGGRRLS--------YFVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLEL 257
            ||.|||::        :|..:|:|..        .|:.::..:|..:.:.....:.:.|:..:|:
Mouse   177 DRFGRRMALWCTSIGVFFFGIASLFI--------FDYLSFMITRFFLVMASSGYFVVVFVYVMEI 233

  Fly   258 VGENYRSFVTVMTCTFYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMR 322
            :|:..|::.::...||:..|.||::..:||.:.|.....|..:....:.|..:::||:|.|||..
Mouse   234 IGKKARTWASIHLNTFFAIGAMLVALASYLLKTWWLYQIILCIVTTPFILCCWMLPETPFWLLSE 298

  Fly   323 GRLEEALKILERMAKVNGREFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTIL 387
            ||.:||...::.||..|.....:.|.| |...:.|.. .|....:....||||....::...|::
Mouse   299 GRYKEAQGTVDTMAVWNKSSSCDLVEL-LSLDVTRSH-NKSPHSIRKHRLADLFHNLDVAKMTLI 361

  Fly   388 ITLSWFANETVYLGLSYYGPAL---GTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMI 449
            :.|.||   |..||...:|..:   ..|:.:...|...:|:|:|:|...::...|||..:.|.::
Mouse   362 VWLDWF---TANLGYYMFGKEVIRRKENEPLYLLLVGAMEIPAYICLCIWLKRVGRRKTMLLFLL 423

  Fly   450 LGGVACVITVMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLG 514
            :..:.|::.|::|.|......::.|:.|:::|:.|..||.:..|||||.||.:.:|:|:.:..:.
Mouse   424 VSSLTCMLHVVMPSDYKTAKRMVALLVKSVISSVFAFIYLYTAELYPTTVRCLAVGSSNMVSHVS 488

  Fly   515 LIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFKDCCR 579
            .|.|||.::..|..:.||.::.|.|::|.|:..|:||||....:..|.|..|:
Mouse   489 SIFIPFTSHFSKVWIFLPQILFGILAILSGLLSLKLPETQDTPMKSTWETTEQ------------ 541

  Fly   580 CAQKPEILSQ-----PASYENLDVLAGSS------TNASEVELELRDSRRVREP--------APR 625
              |.||....     |.|:|..|.....|      .:.:..:.|...|.||...        ||.
Mouse   542 --QVPENKDSLGEGPPDSFERWDSSRALSFAERWGLSRASPDAEKWGSGRVPPDAGKWGAGIAPP 604

  Fly   626 IDE-----RTPLDTTASGSGR--PVHRPSMKRLVRQMSV 657
            :.|     |..|:..:.||||  |.....|:..:..|.|
Mouse   605 VTERGASGRASLEDESGGSGRAPPEKNTEMENEIENMKV 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	113/433 (26%)
		xylE	<306..>342	CDD:182225	14/35 (40%)
Slc22a16	NP_081848.1	MFS_SLC22A16_CT2	118..525	CDD:340933	109/419 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	530..560		8/43 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	579..649		17/65 (26%)