DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CarT and LOC685081

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	XP_008764922.2	Gene:	LOC685081 / 685081	RGDID:	1583222	Length:	621	Species:	Rattus norvegicus

Alignment Length:	548	Identity:	154/548 - (28%)
Similarity:	262/548 - (47%)	Gaps:	41/548 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIP----ELLDLPLEQRKS 99
            ::..:|:||.:|..:...:.:|..: ..|..|:|:||. ..:.:.|.:.    ...:|...::.:
  Rat     7 VMAEVGDFGPFQVRVTILMGIPNFL-SAFFVFSQVFMV-LDEAHHCSVSWVKNHTFNLSAAEQLA 69

  Fly   100 LSIPKELDNDELVYSKCYTYGVNWTQLL-----ESGEEDDLTTMEPNASWPLIKCPQGWEYNTSV 159
            :|||    ||        |.|...:.|:     :|...:|:.:...|.:.   .|..||:|..:.
  Rat    70 VSIP----ND--------TAGRPESCLMFRPPPDSASLEDILSHRFNETQ---ACDSGWDYPENR 119

  Fly   160 VWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAG--SLM 222
            . .|:..:|||||:::.......:....|..||..:||.:.|..|||.|  :.|..||:|  .:.
  Rat   120 P-PSLKNEFDLVCERENLKRTSQSVFMAGLLVGALVFGPVCDWIGRRAS--ILLQVLLSGITGVA 181

  Fly   223 TSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSGVTYL 287
            |:....|..:........:.:........|:..|.||.::|:...|:..:.:..|:|.|:|:.|.
  Rat   182 TAFVPSFELYMVLCFFSAIAVAGYMMSTMILVSEWVGPSWRTRAMVLAQSNFALGLMALAGLAYG 246

  Fly   288 ERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLE 352
            .|:|..|..|.:.|.:....|.:|:||||||||.:||.|||.:::::.|.||||  |.|..|
  Rat   247 VRNWRLLQIIGTTPIFLLVFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGR--PLASEL--- 306

  Fly   353 AQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQYVSF 417
                .::|..:|...:...| ||.|.|.:|..|:::...||.:..:|.||.:.....|.:.|::.
  Rat   307 ----LNQLVPEKTGPSGNAL-DLFRHPQLRKVTLILIAVWFVDSLLYYGLGFQVGDFGLDIYLTQ 366

  Fly   418 FLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSA 482
            .:..|||:|:.|.....|:..||:|....::.|.||.|||.:.:|.|.......|.:|.|...||
  Rat   367 VIFGVVEVPARLSSIPMMEKLGRKWSQLCTLTLAGVMCVIIIFIPGDLPTVATALAVVGKFASSA 431

  Fly   483 SFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTG 547
            :|.|.|.:..||.||.:|..|:|..|....:|.|..|.:..|.:.:..:|::|.|.|.:..|:..
  Rat   432 AFTISYVYTAELLPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHKAIPMLIFGSLPIGAGLLC 496

  Fly   548 LRLPETLHHRLPQTIEEGEEFGKNWQFK 575
            ..||||....|..|:::.|:.|.:.:.:
  Rat   497 ALLPETRGQTLKDTLQDLEQGGPHGEHR 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	151/527 (29%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	113/370 (31%)
LOC685081	XP_008764922.2	2A0119	12..510	CDD:273328	151/527 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020