Protein Alignment CarT and Slc22a23

DIOPT Version :9

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_072146.1
• Gene: Slc22a23 / 64559
• RGDID: 620302
• Length: 689
• Species: Rattus norvegicus
• Alignment Length: 599
• Identity: 141/599 - (23%)
• Similarity: 232/599 - (38%)
• Gaps: 103/599 - (17%)

  Fly    35 DLD-DLLPTIGEF-GKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWC----RIPELLDLP 93
            |.| .:||.:|.. |.|||.||....:||.. .||..|:..|:.|.| ::||    :..||....
  Rat    79 DYDGSVLPFLGGLGGGYQKTLVVLTWIPALF-IGFSQFSDSFLLDQP-NFWCHGAGKGTELAGAT 141

  Fly    94 LEQRKSLSIPKELDNDELVYSKCYTYG--VNWTQLLESGEEDDLTTMEPNASW------------ 144
            :..|                     :|  .|||        ....|....|||
  Rat   142 VTGR---------------------WGDMGNWT--------SPSATPFSTASWGTTSNRSNSSDT 177

  Fly   145 PLIKCPQG------------WEY--NTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYL 195
            |.:..|.|            |:|  .|.:| .::|..:|||||......:...:|..|...|..:
  Rat   178 PPLPSPPGKGNNDSNCECHAWDYGIRTGLV-QNVVSKWDLVCDNAWKVHVAKFSLLVGLIFGYLI 241

  Fly   196 FGLLNDRGGRRLSYFVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGE 260
            .|.:.|..|||......:..:|...|..:||.:...::..|...|..:..:....:.:.:||...
  Rat   242 TGCIADWVGRRPVLLFSVIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPP 306

  Fly   261 NYRSFVTVMTCTFYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRL 325
            ..|..:|::......:|..|:.|:..|.|||..|..:...||....||..:.|||.|||:...:.
  Rat   307 GKRFIITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQF 371

  Fly   326 EEALKILERMAKVNGREFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITL 390
            |.|.|::..:.:.|... ||:....:..::.::..::.||    |.:..:..|.|:....:::.:
  Rat   372 ESAKKLILYLTQKNCVS-PESDIKGVMPELEKELSRRPKK----VCIVKVVGTRNLWKNIVVLCV 431

  Fly   391 SWFANETVY-------LGLSYYGPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSM 448
            :......::       :|.....|.| .|.|..::..|.:.|.|.|.....:...|||..|.|.|
  Rat   432 NSLTGYGIHHCFARSMMGHEVKVPLL-ENFYADYYTMASIALASCLAMCLVVRFLGRRGGLLLFM 495

  Fly   449 ILGGVACVITVML----------PDDAVDETLVLYLVS--KALLSASFLIIYPFA---------- 491
            ||..:|.::.:.|          ||..:...|.:.:..  |...|.:|.|:..||
  Rat   496 ILTALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVF 560

  Fly   492 --GELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETL 554
              .|:.||.:|..|:|......|.|::..|.|....:....|..:|....:::..:..|.|||:.
  Rat   561 FCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESR 625

  Fly   555 HHRLPQTIEEGEEF 568
            ...||:.|..||.:
  Rat   626 DQNLPENIANGEHY 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	134/580 (23%)
		MFS	182..551	CDD:119392	88/399 (22%)
Slc22a23	NP_072146.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		6/25 (24%)
		MFS_SLC22A23	187..608	CDD:341002	97/427 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100