Protein Alignment CarT and SLC22A23

DIOPT Version :9

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_011513103.1
• Gene: SLC22A23 / 63027
• HGNCID: 21106
• Length: 710
• Species: Homo sapiens
• Alignment Length: 693
• Identity: 155/693 - (22%)
• Similarity: 255/693 - (36%)
• Gaps: 154/693 - (22%)

  Fly    35 DLD-DLLPTIGEF-GKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCR----IPELLDLP 93
            |.| .:||.:|.. |.|||.||....:||.. .||..|:..|:.|.| ::|||    ..||..:.
Human    79 DYDGSVLPFLGGLGGGYQKTLVLLTWIPALF-IGFSQFSDSFLLDQP-NFWCRGAGKGTELAGVT 141

  Fly    94 LEQRKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASW-------------- 144
            ...|..                  ..| |||.|        .||....|.|
Human   142 TTGRGG------------------DMG-NWTSL--------PTTPFATAPWEAAGNRSNSSGADG 179

  Fly   145 ----PLIKCP-----------QGWEYNT-------------------SVVWSSIV------IDFD 169
                ||...|           :.|:|..                   ::.|.:..      :::|
Human   180 GDTPPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKCCQQQETGALPWDTDTKRWRPELNWD 244

  Fly   170 LVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTSLSKDFWTWAG 234
            ||||......|...:|..|...|..:.|.:.|..|||......:..:|...|..:||.:...::.
Human   245 LVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFST 309

  Fly   235 SRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSGVTYLERDWVRLSYITS 299
            .|...|..:..:....:.:.:||.....|..:|::......:|..|:.|:..|.|||..|..:..
Human   310 LRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALII 374

  Fly   300 LPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEAQIRRDKLKKQK 364
            .||....||..:.|||.|||:...:.|.|.:::....:.| |..||.....:..::.::..::.|
Human   375 CPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKN-RMNPEGDIKGVIPELEKELSRRPK 438

  Fly   365 KKMANVGLADLCRTPNMRLKTILITLSWFANETVY-------LGLSYYGPALGTNQYVSFFLSAV 422
            |    |.:..:..|.|:....:::.::......::       :|.....|.| .|.|..::.:|.
Human   439 K----VCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLL-ENFYADYYTTAS 498

  Fly   423 VELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVML----------PDDAVDETLVLYLVSK 477
            :.|.|.|.....:...|||..|.|.|||..:|.::.:.|          ||..:.:::      |
Human   499 IALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSV------K 557

  Fly   478 ALLSASFLIIYPFA------------GELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLK 530
            ...|.:|.|:..||            .|:.||.:|..|:|......|.|::..|.|....:....
Human   558 DKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYF 622

  Fly   531 LPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFKDCCRCAQKPEILSQPASYEN 595
            |..:|....:::..:..|.|||:....||:.|..||.:.:......  :..::|.:|
Human   623 LHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPLLPH--KKGEQPLLL-------- 677

  Fly   596 LDVLAGSSTNASEVELELRDSRRVREPAPRIDERTPLDTTASG 638
                    |||     ||:|...:.:.|...| ..|...||:|
Human   678 --------TNA-----ELKDYSGLHDAAAAGD-TLPEGATANG 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	134/604 (22%)
		MFS	182..551	CDD:119392	87/397 (22%)
SLC22A23	XP_011513103.1	2A0119	<243..652	CDD:273328	97/420 (23%)
		MFS	259..>388	CDD:119392	30/128 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010