Protein Alignment CarT and Slc22a17

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001347335.2
• Gene: Slc22a17 / 59049
• MGIID: 1926225
• Length: 627
• Species: Mus musculus
• Alignment Length: 640
• Identity: 160/640 - (25%)
• Similarity: 249/640 - (38%)
• Gaps: 136/640 - (21%)

  Fly    13 DELSELRQRHKPESQPSVDEAFDL---------DDLLPTIGEFGKYQKLLVFGICLPACIPCGFC 68
            ::|...|:|.:.....::..:..|         :.||..:|..|..|:|.: |:|   |:|..|.
Mouse    44 EQLQGERERRREGEGDALGSSLSLAAPPGPLSFEALLAQVGALGGGQQLQL-GLC---CLPVLFV 104

  Fly    69 AFNQLFMADTPDDYWCRIPELLDLPLEQRKSLSIPKELDNDELVYSKCYTYGV------NWTQ-- 125
            |   |.||..|  .:...|.|                         .|: ||.      .|.|
Mouse   105 A---LGMASDP--IFTLAPPL-------------------------HCH-YGALPPNASGWEQPP 138

  Fly   126 -----------LLESGEEDDLTTMEPNASW----PLIKCPQGWEYN-TSVVWSSIVIDFDLVCD- 173
                       |..|.....:|:.:|:.|.    ....|.:.|:|| ..|:.::.:..:|||||
Mouse   139 NSSGVSVAGAALAASAASGVVTSTDPSCSGFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDL 203

  Fly   174 ------QDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATL-LAGSLMTSLSKDFWT 231
                  :.|...:|.|:       |....|...||.|||   .:.|.|| |.|......:.
Mouse   204 GWQVILEQILFILGFAS-------GYLFLGYPADRFGRR---GIVLLTLGLVGPCGVGGAA---- 254

  Fly   232 WAGS-------RVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSGVTYLER 289
             |||       |.::|..:..|....:::.|||.....|..|.:........|..|..|:..:.:
Mouse   255 -AGSSTGIMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSK 318

  Fly   290 DWVRLSYITSLPFYAYFLY----MFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLK 350
            ||..|..:.:.|...:..|    :|:  ||.|||:::.::|||..:|..:|:   |..|....|.
Mouse   319 DWRFLQRMITAPCILFLFYGWPGLFL--ESARWLIVKRQIEEAQSVLRILAE---RNRPHGQMLG 378

  Fly   351 LEAQIRRDKLKK--QKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQ 413
            .|||....:|:.  .....:....|.|....|: .|.:||.  .|.|...:.....|.|..|...
Mouse   379 EEAQEALQELENTCPLPATSTFSFASLLNYRNI-WKNLLIL--GFTNFIAHAIRHCYQPVGGGGS 440

  Fly   414 YVSFFL-SAVVELPSYLCCWYF---MDTWGRRWPLSLSMILGGVACVITV----MLPDDAVDETL 470
            ...|:| |.:....:.|.|.:.   :|.:|||..|.|||.|.|:|.::.:    .|.|.|:....
Mouse   441 PSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNDAAITTFS 505

  Fly   471 VLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVI 535
            ||.|.|.   .||.::....|.|:.||.|||.|:|....:|.||.:..|...........|..|:
Mouse   506 VLGLFSS---QASAILSTLLASEVIPTTVRGRGLGLIMALGALGGLSCPAQRLHMGHGAFLQHVV 567

  Fly   536 MGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFKDCCRCAQKPEILSQP 590
            :...::|..::.:.||||....||:.:.:||          .||   :|.:|.||
Mouse   568 LAACALLCILSIMLLPETKRKLLPEVLRDGE----------LCR---RPSLLRQP 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	113/428 (26%)
		xylE	<306..>342	CDD:182225	12/39 (31%)
Slc22a17	NP_001347335.2	MFS_SLC22A17	170..583	CDD:341003	114/438 (26%)