Protein Alignment CarT and sv2a

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_696434.2
• Gene: sv2a / 568033
• ZFINID: ZDB-GENE-131001-1
• Length: 733
• Species: Danio rerio
• Alignment Length: 754
• Identity: 134/754 - (17%)
• Similarity: 224/754 - (29%)
• Gaps: 282/754 - (37%)

  Fly     5 EDNDGDEYDELSELRQRHKPESQPSVD--------EAFDLDDLLPTIGEFGKYQKLLVFGICLPA 61
            ||:|.|:|...::....::..|:.:.|        |..|.||   .|.| |:||
Zfish    51 EDDDDDDYPVQAQDGSYYRSNSRANDDEGAHSDSTEGHDEDD---EIYE-GEYQ----------- 100

  Fly    62 CIPCGFCAFNQLFMADTPDDY--WCRIPELLDLPLEQRKSLSIPKELDNDEL------VYSKCYT 118
                |....:.:..||.....  ..:..::.....|:||        |.:||      :..:|..
Zfish   101 ----GIPRNDSVEKADRQVGAVGQSQFRDMTQYEGERRK--------DQEELAQQYETILQECGH 153

  Fly   119 YGVNWT-------QLLESG------------EEDDLTTMEPNASWPLIKCPQGWEYNTSVVWSSI 164
            ....||       .|:..|            .|.|:...|||..
Zfish   154 GRFQWTLYFVLGLALMADGVEIFVVGFVLPSAEKDMCLSEPNKG--------------------- 197

  Fly   165 VIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTSLSKDF 229
                          .:|| .:..|..||.:::|.|.||.|||.:..:.|:.....:..:|..:.:
Zfish   198 --------------MLGL-IVYLGMMVGAFVWGGLADRIGRRQTLLISLSINSVFAFFSSFVQGY 247

  Fly   230 WTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLS------------ 282
            .::...|::.|:.|.....|.|....|.:.:..|.......|.|:..|.:..:
Zfish   248 SSFLFCRLLSGVGIGGSIPIVFSYYSEFLAQEKRGEHLSWLCMFWMIGGIYAAAMAWAIIPHYGW 312

  Fly   283 ----GVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGRE- 342
                |..|....|.....:.:.|..|....:..||||||:.|..|:.:||..||:::...|.|.
Zfish   313 SFQMGSAYQFHSWRVFVLVCAFPSVAAIAALTTMPESPRFYLENGKHDEAWMILKQVHDTNMRAK 377

  Fly   343 -FPEAVHLKLEAQIRRDKLKKQKKKMANVG-------------LADLCR----------TPNMRL 383
             :||.|.     .:...|..||..::.::|             |.:|..          .|..|.
Zfish   378 GYPERVF-----SVTTIKTVKQMDELVDMGGEATAWHQRWRIKLTNLFHQVWGNFLTVFNPEYRR 437

  Fly   384 KTILITLSWFANETVYLGLSYYGPAL--------------------------------------- 409
            .|.::...||:....|.||:.:.|.:
Zfish   438 ITYMMMAVWFSMSFSYYGLTVWFPDMIKYLQKQEYSSRTKVFIKEKVEHVTFNFTLENQIHRNGE 502

  Fly   410 ----------------------------------------------------------------- 409
                                                                             
Zfish   503 YFNNKFLNLKMKSMVFEDSLFEECYFEDITSSNTFFRNCTFISTLFYNTDLFKYRLINSKLINST 567

  Fly   410 --------------GTNQYVSFFLS---AVVELPSYLCCWYFMDTWGRRWPLSLSMILGG--VAC 455
                          ..|.|:.:|:|   .:..||..:.....||..||     |.|:.|.  ::|
Zfish   568 FLHNKEGCMLDFSDENNAYMIYFVSFLGTLAVLPGNIVSALLMDKIGR-----LRMLAGSSVISC 627

  Fly   456 VITVMLPDDAVDETLVLYLVSKALLS-ASFLIIYPFAGELYPTQVRGIGIGASSYIGGL----GL 515
            |....|.....:..::..|.....:| ||:..:.....||||:..|....|   ::..|    .:
Zfish   628 VSCFFLSFGNSESAMIALLCLFGGISIASWNALDVLTVELYPSDKRTTAFG---FLNALCKLAAV 689

  Fly   516 IGIP-FITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPET 553
            :||. |.:::|... .:|::........|....|:||||
Zfish   690 LGISIFQSFVGITK-AVPILFASGALAAGSFLALKLPET 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	95/568 (17%)
		xylE	<306..>342	CDD:182225	13/35 (37%)
sv2a	XP_696434.2	synapt_SV2	1..733	CDD:130366	134/754 (18%)