Protein Alignment CarT and Slc22a21

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_062697.1
• Gene: Slc22a21 / 56517
• MGIID: 1929481
• Length: 564
• Species: Mus musculus
• Alignment Length: 542
• Identity: 175/542 - (32%)
• Similarity: 285/542 - (52%)
• Gaps: 18/542 - (3%)

  Fly    35 DLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQRKS 99
            |.|::...:||:|.:|:|:.| :...:.||.||...:.:|:...| ::.||||:.::|....|..
Mouse     3 DYDEVTAFLGEWGTFQRLIFF-LLSASIIPNGFTGLSAVFLTAIP-EHRCRIPDTVNLSSAWRNH 65

  Fly   100 LSIPKELDNDELVYSKCYTYGV----NWTQL-LESGEEDDLTTMEPNASWPLIKCPQGWEYNTSV 159
             |||.|..:...|..||..|.:    |:::| ||.|.:.||..:|..      .|..||||:..:
Mouse    66 -SIPMETKDGPEVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQE------NCLDGWEYDKDI 123

  Fly   160 VWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTS 224
            ..|:||.::||||..|....:..:....|..:|.::.|.|:||.||:...|:.:|.....|.:..
Mouse   124 FLSTIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQV 188

  Fly   225 LSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYR-SFVTVMTCTFYTSGIMLLSGVTYLE 288
            .|.:|..:.....:||:...:.|...|::..|::.::.| .|.|:..|.|:..|.|:|....|..
Mouse   189 FSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFGFMVLPLFAYFI 253

  Fly   289 RDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEA 353
            |:|.||....:||........:.:|||||||:.:||::||..|:.:.||:||...|..:....|.
Mouse   254 REWRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSET 318

  Fly   354 QIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQYVSFF 418
            ...:|   ...||..:..:.||.||||:|:.||:..:.|......|.|||...|.|..|.||:.|
Mouse   319 NKLQD---DSSKKPQSHHIYDLVRTPNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNCF 380

  Fly   419 LSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSAS 483
            |.|.||:|:|:..|..:....||:.::.|:.|||...::..::|.|....:..|.:|.|..::::
Mouse   381 LLAAVEVPAYVLAWLLLQHVSRRYSMAGSLFLGGSVLLLVQLVPSDLHYLSTTLVMVGKFGITSA 445

  Fly   484 FLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGL 548
            :.::|.:..|||||.||.:|:|.||....||.|..|:..|||..:.:||.::||.|::|..:..|
Mouse   446 YSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRRLPYILMGSLTILTAIITL 510

  Fly   549 RLPETLHHRLPQTIEEGEEFGK 570
            ..||:....||:||:|.::..|
Mouse   511 FFPESSGVSLPETIDEMQKVKK 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	130/399 (33%)
		xylE	<306..>342	CDD:182225	16/35 (46%)
Slc22a21	NP_062697.1	2A0119	12..523	CDD:273328	169/522 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	532..564		1/1 (100%)