Protein Alignment CarT and slc22a16

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001020659.1
• Gene: slc22a16 / 557279
• ZFINID: ZDB-GENE-041001-166
• Length: 565
• Species: Danio rerio
• Alignment Length: 575
• Identity: 159/575 - (27%)
• Similarity: 263/575 - (45%)
• Gaps: 70/575 - (12%)

  Fly    30 VDEAFDLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPL 94
            |:..||      .:|.|.::|..|.|.....| |.||......:|:.:|| .:.|..|  |::..
Zfish     5 VERLFD------ELGHFKRFQACLYFAAIFQA-ISCGIHYLASVFLVETP-KFLCNPP--LNITD 59

  Fly    95 EQRKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQ-------- 151
            ...|:||.....|              .||. .::|:...:........|.|..|.:
Zfish    60 VLYKNLSFTSLAD--------------IWTH-YKTGDGPVVVRTSQGDQWELSPCLKALRLDAIN 109

  Fly   152 ---------------GWEYNTSVVWSSIVIDFDLVCDQD-----IYPTIGLAALNTGGPVGVYLF 196
                           .:.|:.|.|..|||.|:||||:::     ..||..|..|     :|..:|
Zfish   110 FQYEFFGNKSVESCGAFVYDHSEVEQSIVTDWDLVCEREWLAKLTQPTFMLGVL-----IGALMF 169

  Fly   197 GLLNDRGGRRLSYFVCLATLLAG---SLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELV 258
            |...||.|||.   |.:||.|..   .:..:.:.:::.:...|.::.........:.|:...|..
Zfish   170 GDAADRIGRRP---VLMATSLCQFIFGVTVAFTGNYYLFVVMRFLLATVSSGYLVVVFVYVTEFT 231

  Fly   259 GENYRSFVTVMTCTFYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRG 323
            |...|::.::.....:..|||:::.|.||.|.|.....|.:|....:.||.:..||:|.:|:.:|
Zfish   232 GIKVRTWTSMHVHAAFAVGIMVVALVGYLVRVWWIYQIILTLSTSPFLLYCWKFPETPFYLMAKG 296

  Fly   324 RLEEALKILERMAKVNGREFPEAVHLK-LEAQIRRDKLKKQKKKM---ANVGLADLCRTPNMRLK 384
            |.:||.::|:.||.:||  .|..:.:. |:....|..||..|:.|   ..:.:.|:..:..|..:
Zfish   297 RYKEAQELLDTMAYING--LPPTLKVSDLQDGCDRTPLKDNKQAMEVEKRLSMLDMFGSLKMAGR 359

  Fly   385 TILITLSWFANETVYLGLSYYGPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMI 449
            :......||.....|...|.....||.|||::.||:..||:||||...:.||.:||:...:.:::
Zfish   360 SATCWAIWFIGSLGYYVFSLGSVNLGGNQYINLFLAGAVEVPSYLIGCFAMDRFGRKKTCAPALL 424

  Fly   450 LGGVACVITVMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLG 514
            ||||||::.:::|.|.....:||.:..|..::.:|.:||.:..|||||.:|.:.:|:.|.:..:|
Zfish   425 LGGVACMLIIVVPQDVEVLAIVLSMTGKFAIAIAFGLIYLYTCELYPTIIRSLAVGSGSMMCRVG 489

  Fly   515 LIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFG 569
            .:..||..||....:.||.:|:|.|:.:.|:..:.|||||...|..|:||.|..|
Zfish   490 SVVAPFCVYLADIWIYLPQLIVGILAFIIGILTMFLPETLGEPLTSTLEEAEALG 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	120/410 (29%)
		xylE	<306..>342	CDD:182225	15/35 (43%)
slc22a16	NP_001020659.1	MFS_SLC22A16_CT2	115..526	CDD:340933	120/420 (29%)