Protein Alignment CarT and slc22a23

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001338637.1
• Gene: slc22a23 / 555979
• ZFINID: ZDB-GENE-030131-3564
• Length: 942
• Species: Danio rerio
• Alignment Length: 704
• Identity: 164/704 - (23%)
• Similarity: 281/704 - (39%)
• Gaps: 125/704 - (17%)

  Fly    20 QRHKPES---QPSVDEAFDL-----DDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMA 76
            :.|.||:   .|...::..|     ..:||::|.||||||.|:....:|| |..||..|:..|:.
Zfish    14 ESHAPENGFVTPETSKSPGLLSQTDGGVLPSVGGFGKYQKQLIVLTWIPA-IFIGFSQFSDNFLL 77

  Fly    77 DTPDDYWCRIPELLDLPLEQRKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPN 141
            ..|    |  ||    |......|     |.......|..:| |||    .|:..:.:.|   |:
Zfish    78 TNP----C--PE----PHNNSSQL-----LTVAPTAVSTVFT-GVN----TEAASQCNCT---PS 119

  Fly   142 ASWPLIKCPQGWEYNTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRR 206
            :    .|...|.|.|       ||..::||||......|...:|..|...|..:.|:|.|..||.
Zfish   120 S----YKLQNGLEQN-------IVTKWNLVCDSAWKIHIAKFSLLVGSIFGYLVLGVLADWFGRH 173

  Fly   207 LSYFVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTC 271
            ....:.:..||...:..:.|.:...:...|...|..:..:....:::.:||....:|..:|::..
Zfish   174 PVLILSVVFLLVFGMTVAFSVNLPMFGTLRFFEGFCLAGITLSLYVLRIELCLPGWRFSITMVAN 238

  Fly   272 TFYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMA 336
            ....:|.:|:.|:..|.|||..|..:...|......|::..|||.||||...:...:..|:||::
Zfish   239 FMMLAGQLLMPGLAALCRDWQILQAVIVCPLLLMLSYIWAFPESLRWLLATQQYSRSKWIMERIS 303

  Fly   337 KVNGREFPE-AVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYL 400
            |.|.....| |..|..|.   ...|:||.||..   :..:..|.|:....:::.::
Zfish   304 KKNNINLQEDAEELMTEL---NGALQKQPKKTC---IVKMVGTRNLWKNIVVLCVN--------- 353

  Fly   401 GLSYYG------------PALGTNQ-----YVSFFLSAVVELPS--YLCCWYFMDTWGRRWPLSL 446
            .|:.||            ..:|..:     |..:::.||:.:.|  :||  ..:...|||..|.:
Zfish   354 SLTGYGIHHCFARSMMEKKTVGFVEKLHDFYAEYYVMAVIAVASCVFLC--PAVALMGRRGGLLM 416

  Fly   447 SMILGGVACVITVML---------------PDDAVDETLVLYLVSKALLS--ASFLIIYPFAGEL 494
            .||:..:|.::.:.|               .|:..|:..|.:.:.....|  .|.|.|: |..|:
Zfish   417 FMIITALASLLQLGLLNLLGKYGDHLSLVHSDELNDKFSVAFSIIGMFSSHAVSNLSIF-FCAEI 480

  Fly   495 YPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLP 559
            .|:.:||.|:|......|.|::..|.:....:....|..:|....:::..:..|.||||.:..||
Zfish   481 TPSVIRGGGLGLVLASAGFGMLTSPIMELHNQKGYFLHHIIFACCTLICIICILLLPETRNQPLP 545

  Fly   560 QTIEEGEEFGK-----------------NWQFKDCCRCAQKPEILSQPASYENLDVLAGSSTNAS 607
            :|:.:||.:.:                 ..:.::..|....|...:.......:|     ||.:|
Zfish   546 ETLSDGESYTRQPLLPPRKPGEQRLLLTKSESREYARVGDTPLHEAAATVVSTMD-----STASS 605

  Fly   608 EVELE-LRDSRRVREPAPRIDERTPLDTTASGSGRPVHRPSMKRLVRQMSVMDT 660
            .|::. |.|:...:|||.  .:...::|..|..|:...:.|::.  ...||:.|
Zfish   606 AVDIHMLIDAPIQQEPAQ--VQLLSMETLTSSQGQDELKQSVEE--HPKSVLGT 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	98/435 (23%)
		xylE	<306..>342	CDD:182225	13/35 (37%)
slc22a23	NP_001338637.1	MFS_SLC22A23	108..523	CDD:341002	101/446 (23%)
		DUF5585	<565..921	CDD:465521	19/100 (19%)