DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CarT and oatx

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	XP_017208528.1	Gene:	oatx / 555218	ZFINID:	ZDB-GENE-070115-1	Length:	567	Species:	Danio rerio

Alignment Length:	561	Identity:	175/561 - (31%)
Similarity:	271/561 - (48%)	Gaps:	56/561 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 DLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQRKSL-- 100
            |||..:|.||::|.:.|..:.:|..:.......|. |.|..|:.: ||||.:.....:...:|
Zfish     5 DLLDEVGGFGRFQMIHVTLLSIPGLLMASQNLLNN-FTAGVPEHH-CRIPNVTTAMNDSTTTLLR 67

  Fly   101 -SIPKELDNDELVYSKCYTY-GVNW---TQLLESGEEDDLTTMEPNASWPLIKCPQGWEYNTSVV 160
             .||  ||: .|..|||..| ...|   |..|..|...:|.|.         .|..||.|:.|..
Zfish    68 AFIP--LDS-SLTLSKCSRYKDTQWHLITDKLSHGNATELQTE---------GCADGWTYDKSEF 120

  Fly   161 WSSIVIDFDLVC--------DQDIYPTIGLAALNTGGPV-GVYLFGLLNDRGGRRL----SYFVC 212
            .||||.::||||        .|.||         .||.: |..:||.|:||.||:.    |||
Zfish   121 ISSIVSEWDLVCTLRPLKQMSQTIY---------MGGVLTGAIIFGGLSDRFGRKALLIWSYF-- 174

  Fly   213 LATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSG 277
             ...|.|| .|:|:..:..:...|.:.|:::..|......:.:|.:....|:.|..::..|:|.|
Zfish   175 -QLALLGS-FTALAPSYVVYCIFRFLTGMSVSGVILNAVSLKVEWIPTKTRTLVGTLSSFFFTFG 237

  Fly   278 IMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGR- 341
            .|:|:||.|..|||.::.....|||:.:|:|.:...||.|||::.||.|||||:|.|:||:||:
Zfish   238 QMVLAGVAYSLRDWRKIQMAVCLPFFIFFMYSWWFSESARWLVLNGRSEEALKLLHRVAKINGKP 302

  Fly   342 EFPEAVHL-KLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYY 405
            |..|.:.| :||:.::::  .:..|.:..|  .||.|||.||..::.:.:.||:....|.||:..
Zfish   303 EMTEKITLEELESHMQKE--VQSSKSIYTV--FDLLRTPTMRKISMCLMVVWFSTSFAYYGLAMD 363

  Fly   406 GPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETL 470
            ....|.|.|:...:...|:.|:.|.....:...|||......:::........:.:|:|......
Zfish   364 LQKFGVNIYLMQVIFGAVDFPAKLVALLMLSFLGRRLTQGACLLVSASIIFANIFVPEDMQVTRT 428

  Fly   471 VLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVI 535
            .|.::.|...||||..:|.|.||||||.:|..|:|..|.:..:|.:..|.:..|......||.::
Zfish   429 ALAVLGKGFTSASFTCVYLFTGELYPTVIRQTGMGFVSTMSRIGSMAAPAVLILDDILPALPSIV 493

  Fly   536 MGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFKD 576
            .|..:::.|:....|||||:..||.||::.||   .|:.|:
Zfish   494 YGGSAVIAGLIAFLLPETLNIPLPDTIDDVEE---KWEKKN 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	166/538 (31%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	113/375 (30%)
oatx	XP_017208528.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.020