DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CarT and CG7084

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	598	Identity:	167/598 - (27%)
Similarity:	291/598 - (48%)	Gaps:	42/598 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SQPSVDEAFDLDD----LLPTIGEFGKYQKLLVF----GICLPACIPCGFCAFNQLFMADTPDDY 82
            ||..||:: :.:|    |:...|..|:||.|..|    |:..     .|...:..:.:|....|:
  Fly    21 SQMDVDDS-EFNDPFQALMEKAGNHGRYQTLYNFVFVGGLAF-----SGAMIYMNIILALNIPDH 79

  Fly    83 WCRIP--ELLDLPLEQRKSLSIPKELDN-DELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASW 144
            ||.:|  |..:..||:.:.:::||:.|| ....:|.|..:.:|::::      .|.:....|.:.
  Fly    80 WCTVPGRENTNFSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEI------TDWSAWNSNLTK 138

  Fly   145 PLIKCPQGWEYNTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSY 209
            ....|..||.|:.:...|:|..|.:.||.:|::.|............|.::.|.:.|..|||..|
  Fly   139 TTEACQNGWSYDKTWYESTIPTDHNWVCAKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVY 203

  Fly   210 FVCLATLLAGSLMTSLSKDFWTW----AGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMT 270
            ::.:.....|.|.:.:....:||    :|   |||||:.:::|.|.||.:|:..|..||.:....
  Fly   204 YISVVFCSLGRLGSIMCTSSYTWFLIMSG---IVGLTVNSLFQSPQIIGMEISREEDRSRIAFFQ 265

  Fly   271 CTFYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERM 335
            ...::.|..|:..:.:..|.|....::||:|.....|:...:.||||||:.:.|..||:..|:::
  Fly   266 SCGWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKI 330

  Fly   336 AKVNGREFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYL 400
            ||:||..| :....:|.....||      |:....|:|.|.....:...|.::..||......|.
  Fly   331 AKINGHRF-DMTEKELAEIYSRD------KQDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYF 388

  Fly   401 GLSYYGPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDA 465
            .|..:...:..|.:::|...::||:|:|:...|..||:|||:..|:|.::..|.|:..::...|.
  Fly   389 TLVLFSSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFVTCLPIIVYSTDE 453

  Fly   466 VDETLVLYLVS--KALLSASFLIIYPFAGELYPTQVRGIGIGASSYI-GGLGLIGIPFITYLGKD 527
            ..|.|::||.:  |.|.:.:|..:.....|:|||.:|..|:...:.: ..:|::. |::.|||..
  Fly   454 RYENLMIYLATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLA-PYLVYLGTT 517

  Fly   528 -NLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFKDCCRCAQKPEILSQPA 591
             :::.|..|:|.|.:|||:..|.||||||.:||.|:||...|||:.:|....:..|..|...:.:
  Fly   518 VDIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDKFFSLPKPPQAAEKDDKLS 582

  Fly   592 SYENLDVLAGSST 604
            |:..|..|..|.|
  Fly   583 SHPELTRLRRSET 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	147/531 (28%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	103/376 (27%)
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	139/504 (28%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	103/368 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375160at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	7	7.070