DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CarT and CG7342

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	555	Identity:	146/555 - (26%)
Similarity:	245/555 - (44%)	Gaps:	68/555 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 DLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCR--IPELLDLPLEQ- 96
            ::|.:|...|:|.:.|.:::...|: ..:......::|..::..| .|||.  :|..::.|::.
  Fly     3 EVDKILEKCGDFSRLQMIMLLLFCV-INVLSALHYYSQTIISFVP-KYWCADGLPASIESPVDSS 65

  Fly    97 ----RKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWEYNT 157
                .:::|.|          :.||:|                                  .|..
  Fly    66 CLPLNRNISTP----------NTCYSY----------------------------------NYEL 86

  Fly   158 SVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLM 222
            .:.:.|...:.|.||......|:|.:....|..||..:.|.|.|..||.....|.....:.|:|:
  Fly    87 YMGYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLL 151

  Fly   223 TSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSF-VTVMTCTFYTSGIMLLSGVTY 286
            |..|.:...:...|:|.|:...:.:.:.:|:.:|.:..:.|:. :::....||..|.|....:..
  Fly   152 TIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAV 216

  Fly   287 LERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKL 351
            |.|.|......||||......:..::|||.:||:.:.:.:.|:..|:|:||:|||...|:.:.:.
  Fly   217 LMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEF 281

  Fly   352 EAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQYVS 416
               |...|..:|.:| |:..|.||.:||.:|..|:::..........|..:|.....||.:.:|.
  Fly   282 ---IEECKCSQQNQK-ASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVM 342

  Fly   417 FFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVIT--VMLPDDAVDETLVLYLVSKAL 479
            |.|||...||:.|......|..||:...|.|::|.|:...:|  ::....|.|:|..| |||.::
  Fly   343 FSLSATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTL-LVSLSV 406

  Fly   480 LSA-SFLIIY----PFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFL 539
            :.. ...:.|    .:|.||.||.|||.|:.|....|........:|.:.......||.:|:|.|
  Fly   407 VGRFGVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVL 471

  Fly   540 SMLGGMTGLRLPETLHHRLPQTIEEGEEFGKN--W 572
            |:||....|.||||||..||.::|:||.||||  |
  Fly   472 SLLGACLCLLLPETLHRTLPTSLEDGENFGKNDRW 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	136/531 (26%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	105/376 (28%)
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	134/529 (25%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	35/149 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	5	5.060