DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CarT and CG7333

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster

Alignment Length:	559	Identity:	145/559 - (25%)
Similarity:	256/559 - (45%)	Gaps:	56/559 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 DLDDLLPTIGEFGKYQK--LLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQR 97
            |...:|...|.:|::|.  ||::|.   ..|......|:|..:..|| ::||...:|..|.:|..
  Fly     2 DFSQVLDKCGNYGRFQVMILLLYGY---TNILGSLHYFSQTLITFTP-EHWCFHADLNGLSVEGI 62

  Fly    98 KSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWEYNTSVVWS 162
            :|:       .:.:..|.|       |.||  |..:....:..|.     || :.|.:|....:.
  Fly    63 RSV-------YENISASSC-------TPLL--GVVNGTGVVSTNR-----KC-RNWIFNRESGYE 105

  Fly   163 SIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATL--LAGSLMTSL 225
            ||..:...|||:..:|.:|.:....|..||..:||.|:|:.||..|  :.:|||  ..|..:||.
  Fly   106 SITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPS--LLMATLCGATGDFITSF 168

  Fly   226 SKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSF-VTVMTCTFYTSGIMLLSGVTYLER 289
            ......:|.||.:.||:...:|.:.:|:..|.:....|:| :.::...||..|:|..........
  Fly   169 VHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIG 233

  Fly   290 DWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEAQ 354
            :|.|..::.|||.....:|.|::.||.:|||.:.:.::|:..|:::||.|.|...|:|..:....
  Fly   234 NWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKY 298

  Fly   355 IRRDKLKKQKKKMANVGLADLCRTPNMR-------LKTILITLSW-FANETVYLGLSYYGPALGT 411
            .|..:|:..|..........:..||.:|       :|:::||||. ..|..:        ..|||
  Fly   299 YRERELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNM--------EGLGT 355

  Fly   412 NQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVIT--VMLPDDAVDETLVLYL 474
            :.:..|..:::|.||:.:......:..||:.....::.:||:....|  ::...|..:..|:|.:
  Fly   356 SPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIAHLDPTENALLLAI 420

  Fly   475 ---VSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPF-ITYLGKDNLKLPLVI 535
               :.:...:.|:.....:|.|:.||.|||..: ::.::.||....:.| :.||.:....||.:.
  Fly   421 MVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAV-SNIHVIGLASSSLAFYVIYLAQYYKPLPSIF 484

  Fly   536 MGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQF 574
            :..|...|....|.|||||:.:||:|:.:||:|..|..|
  Fly   485 ISCLMFFGAGLCLTLPETLNKKLPETLADGEKFALNESF 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	137/535 (26%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	95/385 (25%)
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	137/535 (26%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	95/383 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	4	4.010