DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CarT and CG6126

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster

Alignment Length:	579	Identity:	168/579 - (29%)
Similarity:	287/579 - (49%)	Gaps:	82/579 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SVDEAFDLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLP 93
            :||  :.|:||:..:||||||| .|.|.:.:.:.:..|....:.:.:|..|:
  Fly     2 AVD--YVLEDLMGKLGEFGKYQ-FLQFFLQVLSGLTAGMHMLSLVTVAAVPE------------- 50

  Fly    94 LEQRKSLSIPKELDNDELVYSKCYTYGVN--------WTQ--------LLESGEEDDLTTMEPNA 142
                                .:|:..||:        |..        |..:||.:.....:|::
  Fly    51 --------------------HRCFIEGVDNSSLSVTPWNSSAILAAIPLKPNGELESCLMFDPSS 95

  Fly   143 --SWPLIKCPQGWEYNTSVVWSSIVIDFDLVCDQ----DIYPTIGLAALNTGGPVGVYLFGLLND 201
              :...|.| :.:.|:|:...:|..||::.|||:    .|..|:.:..:.||   .|.|.||.:.
  Fly    96 PGTNTTINC-ERYVYDTTYYKTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTG---AVTLGGLADK 156

  Fly   202 RGGRRLSYFVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPA-VYQIPFIISLELVGENYRSF 265
            .|.:.:..:..|..|:.| :..:...:::::..:|.::|:...| .|...|::::||||...|
  Fly   157 VGRKTVFCWSALFQLIIG-VGVAFIPEYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKR-- 218

  Fly   266 VTVMTCTF---YTSGIMLLSGVTYL--ERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRL 325
             ||...||   :..||||::|...|  :|.|:::.|  .|....:..:.:.:.||||||.|:||.
  Fly   219 -TVCGITFQAVFAGGIMLVAGWGALIPDRQWLQVIY--GLHGCLFLGHWWWLDESPRWLWMQGRA 280

  Fly   326 EEALKILERMAKVNGREFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITL 390
            .||:.|:.:..::||...|    :..|..:::.|.:...::.::.||:||.||||:|:||:.:.|
  Fly   281 AEAVDIVAKGLRINGSGIP----VDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCL 341

  Fly   391 SWFANETVYLGLSYYGPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVAC 455
            .||||..||.|||.....|..|.|:..|:..:||.|||:...:.:|..|||...|..|:.||:.|
  Fly   342 CWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCC 406

  Fly   456 VITVMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPF 520
            ::...:...:...|.|: :..|.|::.||.:||.::.||:||.||...:|..|....|.....|.
  Fly   407 IVAAYIAQGSTTSTAVV-MAGKLLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPL 470

  Fly   521 ITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGK--NWQFKDC 577
            ||.|...:.|:|.|:.|.::::.|...:.||||::..:|::||:||.|||  .| |..|
  Fly   471 ITLLDSFDPKIPAVLFGVVALISGFWVMFLPETMNQPMPESIEDGENFGKGDTW-FSQC 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	153/544 (28%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	116/374 (31%)
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	152/543 (28%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	118/384 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I1021
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		mtm1022
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	7	7.060