DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CarT and CG6006

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster

Alignment Length:	617	Identity:	164/617 - (26%)
Similarity:	273/617 - (44%)	Gaps:	104/617 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 RQRHKPES--------QPSVDEAFDLDDLL-PTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLF 74
            :|...|:|        .|:.||  |..|:: ..:|.:||:|.|:...:.| ..:|..|...:.::
  Fly    58 QQAATPQSPAAAVSGLDPADDE--DETDVIGDLMGHYGKWQLLMTVLLSL-FQVPNTFHISSSIY 119

  Fly    75 MADTPDDYWCRIP-ELLDLPLEQRKSLSIPKELDNDELVYSKCYTY-GVNWTQLLESGEEDDLTT 137
            .| ...|:||:.| :|..:|:...::||  ..:||       |..: |::|:|:  |.|    ||
  Fly   120 QA-ANKDFWCQRPAQLQHMPVATWRNLS--GSVDN-------CRRWEGIDWSQV--SNE----TT 168

  Fly   138 MEPNASWP------LIKCPQGWEY----NTSVVWSSIVIDFDLVCDQDIYPTIG----LAALNTG 188
            :..:...|      |:.| :.|||    |....|:|   .:||||:::....:.    |..:.||
  Fly   169 LPSDWKTPAEMDKKLVAC-EKWEYETNDNVGNTWTS---QWDLVCEKEHLKNVAEMFFLLGVATG 229

  Fly   189 GPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFII 253
            |.:.    |.|:|:.||:...|:.........|...:...|..:...|.::||...:|.....|:
  Fly   230 GIIS----GYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLIL 290

  Fly   254 SLELVGENYRSFVTVMTCTFYTSGIMLLSGVTYLERDWVRLSYITSLP-FYAYFLYMFVMPESPR 317
            ::|.|...:|:...:..........|::||:.||.:|:.||.....:| .:..||: ||:|||||
  Fly   291 AIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGIPGIFLCFLW-FVVPESPR 354

  Fly   318 WLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMR 382
            |||::||::|..:|:|..||.|||:.|....|....|           :.:...:..|.|:..:|
  Fly   355 WLLVKGRIDEVRRIIEAAAKFNGRQLPADYQLTPPTQ-----------ESSTQDVTYLFRSSYLR 408

  Fly   383 LKTILITLSWFANETVYLGLSYYGPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLS 447
            ..:|.....||....||.|:.....:.|.|.|::..|:.:||:|:.....|.:...|::|....:
  Fly   409 RISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLFCAT 473

  Fly   448 MILGGVACVITVMLPD--DAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYI 510
            :|..||||....:...  |.:...:...::.|..:||...|:..:..|||||.:|.:|:||.:..
  Fly   474 LICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVA 538

  Fly   511 GGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFK 575
            .||.||..|:::.|.|....|.:.::...|:.||...|.||||
  Fly   539 AGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGFVVLFLPET---------------------- 581

  Fly   576 DCCRCAQKPEILSQPASYENLDVLAGSSTNAS 607
                           |..:..|...|||.|||
  Fly   582 ---------------AVRQKTDNQGGSSANAS 598

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	148/535 (28%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	104/371 (28%)
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	146/527 (28%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	104/372 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	1	0.950	-	0	Normalized mean entropy	S3605
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	7	7.010