Protein Alignment CarT and slc22a2

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_998315.1
• Gene: slc22a2 / 406424
• ZFINID: ZDB-GENE-040426-2167
• Length: 562
• Species: Danio rerio
• Alignment Length: 578
• Identity: 169/578 - (29%)
• Similarity: 283/578 - (48%)
• Gaps: 35/578 - (6%)

  Fly    37 DDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDL------PLE 95
            :::|...|.||:.|..:....|| ..||..|.....:|...|| ::|||.|.:.::      .|:
Zfish     5 EEILEEAGTFGRSQIRIFCTFCL-VSIPFSFVYVGIVFQGFTP-EHWCRDPGVSEIRERCGWSLQ 67

  Fly    96 QRKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDD-------LTTMEPNASWPLIKCPQGW 153
            ..:..::|....:....||:|..:.|:|.....|.|..|       |:.|      |::.|..||
Zfish    68 DARRATVPLINGSSGASYSQCGRFDVDWNATGLSCENPDGDFNQSQLSVM------PMMSCVDGW 126

  Fly   154 EYNTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLA 218
            ||: .|...|.|.:|||||....|..:..|.|:.|..||....|.|.|:.||..|:.:....:..
Zfish   127 EYD-YVGRQSFVTEFDLVCGDAWYVDMFQATLSIGFLVGSIAIGYLADKYGRMKSFLMTNFFIGV 190

  Fly   219 GSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSG 283
            ..::.:.|.::.:....|.:.|..:...:.:.:::..||||.::|..|.|....|::.||:||..
Zfish   191 TGILVATSPNYISLLVFRALFGFGVKGGWMVGYVLITELVGVDHRRTVGVTYQLFFSMGILLLPL 255

  Fly   284 VTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVH 348
            :.|...:|..|..:.::|:..:..|.:.:||||||||.:.::.||::|.:.:||.|.:...:
Zfish   256 LAYFITNWRWLQVVFTVPYICFLTYYWFIPESPRWLLTQNKIAEAVEITKSIAKENRKTLSK--- 317

  Fly   349 LKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQ 413
             |:|. ::.|.:...    :.....||.:|..:|..|.:::.:||.:..||.||......||.|.
Zfish   318 -KIET-LKDDNIDSG----STASFMDLFKTAKLRTYTFILSFNWFTSAVVYQGLIMRLGILGGNV 376

  Fly   414 YVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKA 478
            ||.|.:|.:||||:.......::..|||.|.:.:.|:.|.||:||..:||........:..|.:.
Zfish   377 YVDFLISGIVELPAAFLILLTIERIGRRLPFATANIVAGAACLITAFIPDSMFWLKSAVACVGRL 441

  Fly   479 LLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITY-LGKDNLKLPLVIMGFLSML 542
            .::.:|.::.....|||||.:|.:|:...|.:..:|.|..||:.| |....|:|||:|.|.|:.:
Zfish   442 GITMAFEMVVFVNTELYPTVIRNLGVSVCSTLCDVGGIVAPFLLYRLAVIWLELPLIIFGALAFV 506

  Fly   543 GGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFKDCCRCAQKPEILSQPASYENLDVLA 600
            .|...|.||||....||:||::.|...:|   |:..:.:|:.|.|......:|.||.|
Zfish   507 AGGLVLLLPETKGVPLPETIDDIEHPNRN---KENPQQSQQLENLMTSDVTKNKDVTA 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	120/399 (30%)
		xylE	<306..>342	CDD:182225	15/35 (43%)
slc22a2	NP_998315.1	MFS_SLC22A1_2_3	116..515	CDD:340937	123/414 (30%)