Protein Alignment CarT and slc22a4

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_957143.1
• Gene: slc22a4 / 393822
• ZFINID: ZDB-GENE-040426-1517
• Length: 553
• Species: Danio rerio
• Alignment Length: 599
• Identity: 166/599 - (27%)
• Similarity: 278/599 - (46%)
• Gaps: 68/599 - (11%)

  Fly    35 DLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQRKS 99
            |.||:...:|.:|.:| |.||.....:.:|.||.....:|:.||| .:.|.|||.:::....|.:
Zfish     3 DYDDITSFLGTWGPFQ-LTVFLALAISILPNGFVGLYIVFVGDTP-AHECLIPEQINISSVWRDA 65

  Fly   100 LSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIK-----CPQGWEYNTSV 159
             :||.::.:..|..|.|..|.::..:.|      .:....||....|.:     |..||.|:...
Zfish    66 -AIPTQMQDGVLKRSSCSRYRLDTLRQL------SMLNYTPNVEVNLSQIETEPCVDGWSYSQEF 123

  Fly   160 VWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTS 224
            ..|:||.::||||:::....:..:....|..||.:|.|.::||.|||...|..:|......|:..
Zfish   124 YQSTIVTEWDLVCEREYKGPLTSSIYFCGVLVGTFLSGQMSDRYGRRPVLFTMMALQTITILIQM 188

  Fly   225 LSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSGV----- 284
            .|..:..::.....||.:..:.|.:.:::..|::....|       ..|.:.|:.:.||:
Zfish   189 FSPSWEVFSAIYFFVGFSGFSNYVVAYVLGSEILSPASR-------VLFGSLGVFMGSGIGQMFF 246

  Fly   285 ---TYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEA 346
               .|..|.|..|....:|....||...:.:||||||||.:||..||..:|.|.|:.|....||.
Zfish   247 PLAAYFIRSWRWLVLTNALTGLLYFPLWWFIPESPRWLLSQGRTAEAEAVLRRAAEKNRVTAPEV 311

  Fly   347 VHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILI-TLSWFANETVYLGLSYYGPALG 410
            :....|.:      :..||::....:.|:....| .:.|||| :|.|     :.:.:|||...|.
Zfish   312 IFSSSEIE------EAAKKRIQKHSILDILSNCN-AVSTILICSLLW-----MVITMSYYALILN 364

  Fly   411 T-----NQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETL 470
            |     |.|::||||||||:|:|:.....:....||...:.:::|||....|..::|.:......
Zfish   365 TTNLHGNPYLNFFLSAVVEVPAYIIAALLLRFCSRRICQASTLLLGGALIFIIQLIPTELQGLAT 429

  Fly   471 VLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVI 535
            .|.::.|..::|:|.::|....||:||.||.:.:|:.|....:|.|..|||.|||.....:|.::
Zfish   430 ALEMLGKLCVTAAFCVVYAVTSELFPTVVRNMAMGSCSMTARIGSIISPFIIYLGNYYRYIPYIV 494

  Fly   536 MGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFKDCCRCAQKPEILSQPASYENLDVLA 600
            :|.|::..|:..|.|||:....||:||.:.:      ..:...||.:.|               |
Zfish   495 IGGLALFSGVMSLLLPESKGKVLPETIAQMQ------SVRGLRRCRKPP---------------A 538

  Fly   601 GSSTNASEVELELR 614
            .|:.:.|:|..|::
Zfish   539 ASTEDKSKVLQEVK 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	119/412 (29%)
		xylE	<306..>342	CDD:182225	17/35 (49%)
slc22a4	NP_957143.1	MFS_SLC22A4_5_OCTN1_2	106..510	CDD:340934	120/422 (28%)