Protein Alignment CarT and SLC22A10

DIOPT Version :9

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001034841.3
• Gene: SLC22A10 / 387775
• HGNCID: 18057
• Length: 541
• Species: Homo sapiens
• Alignment Length: 573
• Identity: 150/573 - (26%)
• Similarity: 242/573 - (42%)
• Gaps: 70/573 - (12%)

  Fly    37 DDLLPTIGEFGKYQKL-LVFGICLP---------------ACIPCGFCAFNQLFMADTPDDYWCR 85
            ::||..:|..|::|.| |||  .||               |.||...|              |.
Human     4 EELLSQVGGLGRFQMLHLVF--ILPSLMLLIPHILLENFAAAIPGHRC--------------WV- 51

  Fly    86 IPELLD-----------LPLEQRKSLSIPKELDNDELVYSKCYTYGVNWTQLL------ESGEED 133
              .:||           |..:....:|||  ||:: |...||..:.....|||      .|..|.
Human    52 --HMLDNNTGSGNETGILSEDALLRISIP--LDSN-LRPEKCRRFVHPQWQLLHLNGTIHSTSEA 111

  Fly   134 DLTTMEPNASWPLIKCPQGWEYNTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGL 198
            |   .||        |..||.|:.|...|:||..:|||||.....::....|.||..||..:.|.
Human   112 D---TEP--------CVDGWVYDQSYFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGH 165

  Fly   199 LNDRGGRRLSYFVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYR 263
            ::||.|||.....||..|.......:.:..|..:...|.:.|.:...:.....:...|.:..|.:
Human   166 VSDRFGRRFILRWCLLQLAITDTCAAFAPTFPVYCVLRFLAGFSSMIIISNNSLPITEWIRPNSK 230

  Fly   264 SFVTVMTCTFYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEA 328
            :.|.:::....:.|.::|.|:.|:.|||..|..:.|:||:.:||....:.||.|||::..:|:|.
Human   231 ALVVILSSGALSIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEG 295

  Fly   329 LKILERMAKVNG-REFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSW 392
            ||.|.::|:.|| :...|.:::::.....:::|...:.|..   :.||.|.|:||.:..::....
Human   296 LKALRKVARTNGIKNAEETLNIEVVRSTMQEELDAAQTKTT---VCDLFRNPSMRKRICILVFLR 357

  Fly   393 FANETVYLGLSYYGPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVI 457
            |||...:.|.......:|:|.::...|...|.|.........::..|||....|.|.|.|::.:.
Human   358 FANTIPFYGTMVNLQHVGSNIFLLQVLYGAVALIVRCLALLTLNHMGRRISQILFMFLVGLSILA 422

  Fly   458 TVMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFIT 522
            ...:|.:.....:.|..:.....:|:|..:.....||.||.:|....|.......:|....|.:.
Human   423 NTFVPKEMQTLRVALACLGIGCSAATFSSVAVHFIELIPTVLRARASGIDLTASRIGAALAPLLM 487

  Fly   523 YLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFK 575
            .|......||.:|.|...::||:....||||.:..||.||::.|...||.:.|
Human   488 TLTVFFTTLPWIIYGIFPIIGGLIVFLLPETKNLPLPDTIKDVENQKKNLKEK 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	142/550 (26%)
		MFS	182..551	CDD:119392	90/369 (24%)
SLC22A10	NP_001034841.3	2A0119	11..526	CDD:273328	142/550 (26%)
		MFS	143..516	CDD:119392	90/375 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.010