DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CarT and CG42269

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_648019.2	Gene:	CG42269 / 38689	FlyBaseID:	FBgn0259164	Length:	662	Species:	Drosophila melanogaster

Alignment Length:	611	Identity:	206/611 - (33%)
Similarity:	317/611 - (51%)	Gaps:	50/611 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SVDEAFDLDDLLPTIGEFGKYQKLLVFGIC-LPACIPCGFCAFNQLFMADTPDDYWCRIPELLDL 92
            |:..:.|.||:||.|||||:|||||.  || :|......|..|:|:|:...|:.:||.:|||..|
  Fly    65 SLPPSMDFDDILPLIGEFGRYQKLLF--ICMIPFSFFVAFVYFSQIFLTLIPEQHWCHVPELDGL 127

  Fly    93 PLEQRKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWEYN- 156
            .:|.|.:||||  :.|.|  |:.||.|.||:|.:|..|:      :..:..||.:||..||.||
  Fly   128 DVEARLALSIP--MTNGE--YNNCYMYDVNYTDILAQGK------VMADPKWPQVKCRHGWSYNF 182

  Fly   157 TSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSL 221
            |.:.::::..:.:.|||....||...:....|..||..|||.:.||.||       :..|:..::
  Fly   183 TEIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGR-------IPALIGTNM 240

  Fly   222 M-------TSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMT-CTFYTSGI 278
            |       |:...:||.:|..|..||......:.:.:|:.||.||..||:||..|: ..|:|...
  Fly   241 MGLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAA 305

  Fly   279 MLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREF 343
            .||..:.|...||..|:.:||.|........||:|||.|||:.:|::::|:.||:::.|.|||:.
  Fly   306 CLLPWIAYFLADWKLLAIVTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQV 370

  Fly   344 PEAVHLKLEAQIRRDKLKKQKKKMANVG---LADLCRTPNMRLKTILITLSWFANETVYLGLSYY 405
            |...:     ||..|..|:.:::.|..|   :.||.::|.:|..|:|:.:.|.|...|:.|....
  Fly   371 PPQTY-----QIFTDSCKRMQEQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRN 430

  Fly   406 GPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETL 470
            ..:||.:.:.:|.|:...|||:.......:|.:||||....||:|.||..::..::|.......|
  Fly   431 VGSLGLDIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLATVVPVGIYSAAL 495

  Fly   471 VLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVI 535
            .  ::.:..::.|:.|...:|.|:.||.||...:.....:|.:..|..||:.||...:..|||:|
  Fly   496 A--IMGRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALPLII 558

  Fly   536 MGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKN---WQFKDCCRCAQKPEILSQPASYENLD 597
            :|.|.::||:..|.|||||:|.||||:.:|||||:.   |.|....:.....|...:.|..|.:.
  Fly   559 LGILGIIGGLLALLLPETLNHVLPQTLSDGEEFGRGQSIWDFPCLAKQVDDDEDEKRNADVEEVR 623

  Fly   598 VLA-------GSSTNASEVELELRDS 616
            ..|       |:|.||| ...|||.|
  Fly   624 SQAFVRGTQTGASLNAS-TGGELRSS 648

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	177/529 (33%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	115/379 (30%)
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	160/497 (32%)
CG42269	NP_648019.2	MFS	206..545	CDD:119392	104/352 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	1	0.900	-	-		E33208_3B9N9
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	7	6.960