Protein Alignment CarT and Slc22a14

DIOPT Version :9

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001032838.1
• Gene: Slc22a14 / 382113
• MGIID: 2685974
• Length: 629
• Species: Mus musculus
• Alignment Length: 689
• Identity: 160/689 - (23%)
• Similarity: 285/689 - (41%)
• Gaps: 159/689 - (23%)

  Fly    19 RQRHKPE-SQPSVDEAFDL------------DD----LLPTIGEFGKYQKLLVFGICLPACIPCG 66
            |..|:.| |.||.:.:.::            ||    ::..|||||.:|..||....:|:.:..
Mouse    17 RDTHRHEISFPSQNWSLEMLLRRLKAIDARRDDKFASVMDAIGEFGTFQWRLVVLTFIPSILST- 80

  Fly    67 FCAFNQLFMADTPDDYWCRIPELLD----LPLEQRKSLSIPK---------------ELDNDELV 112
            |..|:..|:......| |....:|:    |..:::.:|::|:               ..|.|.::
Mouse    81 FFIFSHHFLLTAQRPY-CNTSWILEVGPNLTEDEQLNLTLPRAPNGSFLTCLMYIPVPWDLDSII 144

  Fly   113 YSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWEYNTSVVWSSIVIDFDLVCDQDIY 177
            :     :|:|:|:                      .|..||.|..:.. .|::.:|||||..:..
Mouse   145 H-----FGLNYTE----------------------TCKFGWIYPFAHT-RSLINEFDLVCGNEPN 181

  Fly   178 PTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLM----TSLSKDFWTWAGSRVI 238
            ...||....:|...|..|||.|:|:.||   |.:.|.:|| |.|:    |:....|:.:...|..
Mouse   182 KENGLTVFLSGVLTGSLLFGFLSDKLGR---YPIILLSLL-GFLIFGFGTAFVSSFYQYLFFRFF 242

  Fly   239 -----VGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSGVTYLERDWVRLSYIT 298
                 ||..|.:|    .::...|||| :|:...::..:|.|.|::||:|:.|....|..|..:.
Mouse   243 VAQASVGYAICSV----SLVMEWLVGE-HRAQAVILQHSFLTIGVILLTGLAYKVVHWRLLCLLG 302

  Fly   299 SLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEAQIRRDKLKKQ 363
            .:|.:.....::|:.||||||::||::|||.|:|...|:||.:..|  ::|..|.||       .
Mouse   303 GMPMFPLICNIWVLRESPRWLMVRGKVEEAKKVLCYAAEVNKKTIP--LNLLNELQI-------S 358

  Fly   364 KKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQYVSFFLSAVVELPSY 428
            .||:|...:.|.|...::....:.|...||....:...|:......|.:.|....:.::|.:|:.
Mouse   359 GKKVAKASILDFCTNQHLFKVVLAIGCVWFTVSYISFTLNLKMNDFGLDVYFVQMVRSIVAVPAR 423

  Fly   429 LCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGE 493
            |||...::.:||:|.|:|::.|....|:..:.||.:.....::..::::..::.:..|.:.:..|
Mouse   424 LCCIILLEYFGRKWALNLTLFLVTSMCLFLLFLPQEPKSTIILTLMLAEFSMAGTLSIFFIYTAE 488

  Fly   494 LYPTQVRGIGIGASS--YIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHH 556
            |.||.:|..|:|..|  ::.|    .|..:....:...:||:..
Mouse   489 LLPTVLRSTGLGMVSLAWVAG----AISSVAIFKQTKTQLPIFF--------------------- 528

  Fly   557 RLPQTIEEGEEFGKNWQFKDCCRCAQKPEILSQPASYENLDVLAGSSTNASEVELELRDSRRVRE 621
                                ||.|.    :|:  ..:.:|....||.:....:|..:|||   .|
Mouse   529 --------------------CCLCC----VLA--LCFSSLVPETGSQSLRDSIEYNIRDS---IE 564

  Fly   622 PAPRIDERTPLDTTASGSGRPVHRPSMKRLVRQMSVMDT 660
            |..| ::..|:         .:...||..:|....|.:|
Mouse   565 PKDR-NKDVPM---------VIAEESMSDIVADSEVTNT 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	131/546 (24%)
		MFS	182..551	CDD:119392	98/379 (26%)
Slc22a14	NP_001032838.1	2A0119	59..553	CDD:273328	138/592 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910