DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CarT and CG8654

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_001246441.1	Gene:	CG8654 / 37275	FlyBaseID:	FBgn0034479	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	536	Identity:	148/536 - (27%)
Similarity:	243/536 - (45%)	Gaps:	63/536 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 DDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQRKSLS 101
            |.::..||:|.:|| |..|.|.|......|:.....:|:| .|....|:...:.| |.
  Fly    22 DPIISQIGDFRRYQ-LFFFFIVLLCKFGTGWHTLGHIFLA-APTPLSCKTENVTD-PC------- 76

  Fly   102 IPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWEYNTSVVWSSIVI 166
                  :||                                      |.: .|::|||..|:|:.
  Fly    77 ------SDE--------------------------------------CSE-TEFDTSVFQSTIIT 96

  Fly   167 DFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTSLSKDFWT 231
            :::|.|:.....::..:.:..|...|..|||:..||.|||.::..|....|...|:..:|..:|.
  Fly    97 EWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWF 161

  Fly   232 WAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSGVTYLERDWVRLSY 296
            :...|.:|.:.........|::.:|:||...|..|.::....:..|...|:...|..|:|....:
  Fly   162 YCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQF 226

  Fly   297 ITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEAQIRRDKLK 361
            ..::....:.:|::::|||||||...|:|::::||||::||.| :...|.:..::||.......:
  Fly   227 SITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCN-KAPTETIRPEIEAAYGALAAR 290

  Fly   362 KQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQYVSFFLSAVVELP 426
            :..||..   :.||.|||.||:|||.:..:|.....||.|.:.|..|||.|.::|..::|.|.:|
  Fly   291 QPVKKGT---VVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIP 352

  Fly   427 SYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSAS--FLIIYP 489
            ....|.......||:..|.||.....:..::...|...|  |.:.:...:..|..||  |..:|.
  Fly   353 GTCLCALMTKYLGRKKTLLLSNGCSALGLILLACLSTQA--EAVRVTCATIGLFGASITFPNVYL 415

  Fly   490 FAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETL 554
            :.|||:||.||..|:|..|.:|.:|.|..|.|..|....|.:..:|.|..|:|..:..:.||||.
  Fly   416 YGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILAMLGTIFLPETR 480

  Fly   555 HHRLPQTIEEGEEFGK 570
            ...||:|:|:||.||:
  Fly   481 GTPLPETLEDGETFGR 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	140/518 (27%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	108/370 (29%)
CG8654	NP_001246441.1	SP	85..487	CDD:273317	121/407 (30%)
CG8654	NP_001246441.1	MFS	87..477	CDD:119392	115/395 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	1	0.900	-	-		E33208_3B9N9
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I1021
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	7	6.960