DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CarT and Balat

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster

Alignment Length:	571	Identity:	235/571 - (41%)
Similarity:	351/571 - (61%)	Gaps:	36/571 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 DLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQR-- 97
            |.|::|..:|.||.|||:::..:.|||.:||.|.|::|||:|.|| .::||:|||  .|..|.
  Fly     2 DFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATP-QHFCRVPEL--EPWTQDYV 63

  Fly    98 ---KSLSIPKELDNDELVYSKCYTYGVNWTQL-----------LESGEEDDLTTMEPNASWPLIK 148
               |:||||:   |....|::|..|..|:|.:           |...:.:||..::|:.: .::.
  Fly    64 QLVKNLSIPR---NRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTT-QVVP 124

  Fly   149 CPQGWEYNTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCL 213
            |..||.|:.|:..|::|.:::||||:....|:.|.....||.:|.|:||.|.|..|||.|::..|
  Fly   125 CQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYL 189

  Fly   214 ATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGI 278
            ...:.....::.:.:::||.|.|.:||||:||:...|:::::||||...|.|.|:::...|:.|:
  Fly   190 LLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNIAYSLGL 254

  Fly   279 MLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNG--- 340
            ::|:||.|:.|||..||...|:|....|...||:|||||||:..|:...|:|||:.||:|||
  Fly   255 VVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGVRV 319

  Fly   341 -REFPEAVHLKLEAQIRRDKLKKQKKKM-ANVGLADLCRTPNMRLKTILITLSWFANETVYLGLS 403
             |:|.|    :|:.::...:..:.|..| .:.|:.||.|.||||.||::|||.||||.:||:|||
  Fly   320 NRDFVE----RLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSVYVGLS 380

  Fly   404 YYGPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDE 468
            ||.||||.::..:|||:..||||:||..|..:..:||||.|.:||::||||||.|.:.|    |.
  Fly   381 YYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVATFLYP----DI 441

  Fly   469 TLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPL 533
            ||:||.|.|..:|:||:::...|.|||||.|||:|:..||.|..:|.|.||.|.::|:..|.|||
  Fly   442 TLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINHMGQQMLVLPL 506

  Fly   534 VIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFKDCCRCAQKP 584
            ::||.|.:|||...|.||||.:..||||:||||....::....|....:||
  Fly   507 IVMGALLILGGFASLLLPETRNRNLPQTLEEGEAVPLSFLLCCCVESERKP 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	223/537 (42%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	164/373 (44%)
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	175/403 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	274	1.000	Domainoid score	I937
eggNOG	1	0.900	-	-		E33208_3B9N9
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I1021
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D100583at6656
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		otm14734
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	10	9.980