Protein Alignment CarT and Slc22a14

DIOPT Version :9

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001101663.2
• Gene: Slc22a14 / 316061
• RGDID: 1306470
• Length: 630
• Species: Rattus norvegicus
• Alignment Length: 681
• Identity: 165/681 - (24%)
• Similarity: 290/681 - (42%)
• Gaps: 109/681 - (16%)

  Fly     5 EDNDGDEYDELSELRQRHKPE-SQPSVDEAFD--------LDD--------LLPTIGEFGKYQKL 52
            |.|...|:.. .:.|..|:.| |.||.:.:.:        |||        :|..|||||.:|..
  Rat     4 EQNSNTEFGS-QDSRDSHRHELSYPSQNWSLEMLLRRLKALDDRRDDKFASVLGAIGEFGTFQWR 67

  Fly    53 LVFGICLPACIPCGF-CAFNQLFMADTPDDYWCRIPELL----DLPLEQRKSLSIPK-------- 104
            ||....:|:.:...| .:.:.|..|..|   :|....:|    :|..:::.:|::|:
  Rat    68 LVALTFIPSILSTFFLLSHHFLLTAQRP---YCNTSWILQVGPNLTEDEQLNLTVPRAPNGSFLT 129

  Fly   105 -------ELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWEYNTSVVWS 162
                   ..|.|.:|:     :|:|:|:                      .|..||.|..:.. .
  Rat   130 CLMYIPVPWDLDSIVH-----FGLNYTE----------------------TCKHGWIYPFAHT-R 166

  Fly   163 SIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLM----T 223
            |:..:|||||..:.:...|.....:|...|..|||.|:|:.||   |.:.|.:|| |.|:    |
  Rat   167 SLTNEFDLVCGNEPHEENGQTVFLSGILTGSLLFGFLSDKLGR---YPIILLSLL-GILIFGFGT 227

  Fly   224 SLSKDFWTWAGSRVI-----VGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSG 283
            :....|:.:...|..     ||..|.:|    .::...||||:....:.:..| |:|.|::||:|
  Rat   228 AFVNSFYQYLFFRFFVAQASVGYAICSV----SLVMEWLVGEHRAQAIILQHC-FFTIGVILLTG 287

  Fly   284 VTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVH 348
            ..|....|..|..:..:|.:.....::|:.||||||:::|::|||.|:|...|:||.:..|  ::
  Rat   288 FAYKINHWRLLFLLGGVPMFPLICNIWVLQESPRWLMVKGKVEEAKKVLCYAAEVNKKTIP--LN 350

  Fly   349 LKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLS--WFANETVYLGLSYYGPALGT 411
            |..|.|:        ..|.|...:.|.  ..|..|..:::.:.  ||....|.|.||......|.
  Rat   351 LLNELQL--------PGKKAKASILDF--YTNQHLFKVVLAMGCVWFTVSYVSLTLSLKMKDFGL 405

  Fly   412 NQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVS 476
            :.|....:..:..:|:.|||...::.:||:|.|:|::.|....|:..:.:|::....|:::.::.
  Rat   406 DIYFIQVVPCITAVPARLCCILLLEYFGRKWSLNLTLSLVTFTCLSLLFVPEELKSTTILMLVLG 470

  Fly   477 KALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSM 541
            :..::.:..|.:.:..||.||.:|..|:|..|.....|  .|..:....:...:||:.......:
  Rat   471 EFSMAGTVSIFFIYTAELLPTILRSTGLGMVSIAWTAG--AISSLAIFKQTKTQLPIFFCCLCCI 533

  Fly   542 LGGMTGLRLPETLHHRLPQTIE--EGEEFGKNWQFKDCCRCAQKPEILSQPASYENL--DVLAGS 602
            |.......:|||.:..|..:||  ..:......:.||..:.....|.:...|:...|  :.:..:
  Rat   534 LALCFSSLVPETGNQPLRDSIEYCSRDSLEHKDKSKDSSKVLMAEESMCDVAADSVLTKNTMFNA 598

  Fly   603 STNASEVELELRDSRRV--REPAPRIDERTP 631
            .|..||.:..|..:..|  ||...::.|..|
  Rat   599 MTLKSETDSFLNMALEVPNRESPVQLPEDHP 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	135/547 (25%)
		MFS	182..551	CDD:119392	97/379 (26%)
Slc22a14	NP_001101663.2	MFS	147..527	CDD:421695	110/425 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010