Protein Alignment CarT and Slc22a4

DIOPT Version :9

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_062661.1
• Gene: Slc22a4 / 30805
• MGIID: 1353479
• Length: 553
• Species: Mus musculus
• Alignment Length: 562
• Identity: 171/562 - (30%)
• Similarity: 292/562 - (51%)
• Gaps: 36/562 - (6%)

  Fly    35 DLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQRKS 99
            |.|:::..:||:|.:|:|:.| :...:.||.||...:.:|:|.|| ::.|.:|:.::|....|..
Mouse     3 DYDEVIAFLGEWGPFQRLIFF-LLSASIIPNGFNGMSVVFLAGTP-EHRCLVPDTVNLSSSWRNH 65

  Fly   100 LSIPKELDNDELVYSKCYTYGV----NWTQL-LESGEEDDLTTMEPNASWPLIKCPQGWEYNTSV 159
             |||.|..:...|...|..|.:    |::.: ||.|::.||..:|..:      |..||||:..:
Mouse    66 -SIPLETKDGRQVPQSCRRYRLATIANFSAMGLEPGQDVDLEQLEQES------CLDGWEYDKDI 123

  Fly   160 VWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTS 224
            ..|:||.:::|||:.|....:..:....|...|.::.|.|:||.||:...|..:|.....|.:..
Mouse   124 FLSTIVTEWNLVCEDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFSFVQI 188

  Fly   225 LSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYR-SFVTVMTCTFYTSGIMLLSGVTYLE 288
            .|.::..:.....|||:...:.|.:.||:..|::.::.| .|.|:..|||:..|.|:|....|..
Mouse   189 FSTNWEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRIIFSTLGVCTFFAIGYMVLPLFAYFI 253

  Fly   289 RDWVRLSYITSLP-FYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLE 352
            |||..|....:|| .:...|:.|: |||||||:.:.|..||.:|:::.||:|....|..:...||
Mouse   254 RDWRMLLLALTLPGLFCVPLWWFI-PESPRWLISQRRFAEAEQIIQKAAKMNSIVAPAGIFDPLE 317

  Fly   353 AQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQYVSF 417
            .| ..:.||:||     |.:.||.||.|:...|::..:.|......|..||...|.|..:.|::.
Mouse   318 LQ-ELNSLKQQK-----VIILDLFRTRNIATITVMAVMLWMLTSVGYFALSLNVPNLHGDVYLNC 376

  Fly   418 FLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSA 482
            |||.::|:|:|...|..:.|..||:.::..:..||...::..::|:|....::.|.::.|..:::
Mouse   377 FLSGLIEVPAYFTAWLLLRTLPRRYIIAGVLFWGGGVLLLIQVVPEDYNFVSIGLVMLGKFGITS 441

  Fly   483 SFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTG 547
            :|.::|.|..|||||.||.:.:|.:|....:|.|..|:..|||..|..||.::||.|::|.|:..
Mouse   442 AFSMLYVFTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIGIIT 506

  Fly   548 LRLPETLHHRLPQTIEEGEE---FGKNWQFKDCCRCAQKPEI 586
            |..||:....||:.:|:.::   |          ||.:|..:
Mouse   507 LFFPESFGVTLPENLEQMQKVRGF----------RCGKKSTV 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	164/523 (31%)
		MFS	182..551	CDD:119392	116/370 (31%)
Slc22a4	NP_062661.1	2A0119	12..519	CDD:273328	163/522 (31%)
		MFS	123..510	CDD:119392	123/393 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9078
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D375160at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.930